Corneal Edema After Phacoemulsification

Central Corneal Thickness Assessment After Phacoemulsification: Subluxation Versus Divide-and-Conquer

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03689270

Acronym

COPHA

Enrollment

Registered

2018-09-28

Start date

2015-01-31

Completion date

2015-12-31

Last updated

2018-09-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract

Keywords

subluxation, Divide and conquer

Brief summary

To compare the impact of two phacoemulsification techniques (subluxation versus divide-and-conquer) on postoperative corneal edema at postoperative hour 1 and day 4.

Detailed description

Phacoemulsification is the procedure of choice for most surgeons performing cataract surgery. Alternative techniques have been in development over the last twenty years, with the hope of optimizing operating times, total ultrasound energy used, patient safety, patient satisfaction and visual recovery associated with cataract surgery. Divide-and conquer is the parent nucleofracture technique.The subluxation technique is a newer technique that is less frequently used because of an increased risk of corneal endothelium damage. The aim of this comparative study was to evaluate corneal edema immediately after surgery performed with the subluxation technique versus divide-and-conquer. Corneal edema was determined by measuring central corneal thickness (CCT).

Interventions

PROCEDURESubluxation

One pole of The nucleus is hydrodissected until it lilts above the capsular bag. The tilted nucleus is rotated to face the incision and remaining half nucleus is then tumbled and emulsification continues from the opposite equator outside in until complete.

PROCEDUREDivide and conquer

Cataract nucleus is fragmented into 4 pieces then aspirated by ultrasonic vibration

Study design

Observational model

OTHER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* The presence of a senile cataract with equivalent grades and history of visual acuity regression * Informed written consent

Exclusion criteria

* Patients with total white cataract * With history of ocular surgery and other eye diseases (corneal pathology, uveitis, glaucoma) * With systemic diseases with the potential to affect vision

Design outcomes

Primary

Measure	Time frame	Description
Corneal edema preoperative	Day 1	Central corneal thickness measurements were taken preoperatively

Secondary

Measure	Time frame	Description
Corneal edema postoperative	Day 4	Central corneal thickness measurements were taken postoperative day 4

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026