Infertility
Conditions
Brief summary
It's well known, endometritis affects reproductive outcomes. Though CD138 counting as one new diagnosis measure for endometritis, diagnostic criterion of this measure isn't consistent. And if the CD138 counting is correlation to the outcome of reproductive is not clear. Firstly, This study aims to explore the relationship between endometrial CD138 count and pregnancy outcome following frozen embryo transfer in natural cycles. Secondly , the investigators want to find a cut-off value which is related to reproduction outcome.
Interventions
PROCEDUREEndometrial biopsies
Endometrial biopsy was performed precisely 7 days after LH surge (LH+7)
Sponsors
Reproductive & Genetic Hospital of CITIC-Xiangya
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 38 Years
Healthy volunteers
No
Inclusion criteria
* age between20 and 38 years; * regular menstrual cycles; * body mass index (BMI) ranged from 18 to 25
Exclusion criteria
* uterine abnormalities; * intrauterine adhesions（moderate - severe）, advanced endometriosis, adenomyosis, untreated hydrosalpinx, uterine fibroids (submucosal fibroids, nonmucosal fibroids \>4.0 cm and/or endometrial pressure)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CD138 counting | 7 days after LH surge (LH+7) |
| clinical pregnancy rate | about 28 days after embryo transfer |
Countries
China
Outcome results
None listed