Premature Rupture of Membrane
Conditions
Brief summary
Prelabour rupture of membrane is defined as rupture of membranes prior to the onset of labour. Approximately 8% of pregnant women at term experience PROM, but the decision as to how term PROM should be managed clinically remains controversial, and there is wide variation in practice with no clear consensus on what constitutes optimal treatment. Although for the majority of women labour will start spontaneously within 24 hours following term PROM, up to 4%of women will not experience spontaneous onset of labour within seven days.
Interventions
PROCEDUREinduction of labor
oxytocin intravenous drip
PROCEDUREfollow up
hospitalization and antibiotics
Sponsors
Assiut University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Healthy volunteers
No
Inclusion criteria
* Preterm premature rupture of membranes. * Singleton gestation. * Pregnant between 34 weeks 0 days to 36 weeks 6 days.
Exclusion criteria
* Non cephalic presentation. * fetal distress. * Labour on admission. * Medical or obstetric complications such as(suspected chorioamnionitis ,hypertensive disorders, diabetes mellitus , active genital herpes , placenta previa , infection, meconium stained amniotic fluid ,severe fetal anomalies).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the percentage of patients with chorioamnionitis | 24 hours | Clinical chorioamnionitis is defined in the absence of other causes of hyperpyrexia by a temprature of \>38 C with either uterine tenderness , leucocytosis , maternal or fetal tachycardia , or foul smelling vaginal discharge |
Outcome results
None listed