Pratical Assessment of DSAEK in the Management of Endothelial Decompensation Following Penetrating Keratoplasty

Pratical Assessment of Descemet'Sstripping Automated Endothelial Keratoplasty (DSAEK) in the Management of Endothelial Decompensation Following Penetrating Keratoplasty

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03687996

Acronym

MADE

Enrollment

Registered

2018-09-27

Start date

2015-01-01

Completion date

2016-07-31

Last updated

2023-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Descemet's Stripping Automated Endothelial Keratoplasty

Brief summary

Reporting our anatomical and functional results and the possible complications of the first six Descemet's stripping endothelial keratoplasty (DSAEK) performed in our department secondary to endothelial decompensation after penetrating keratoplasty.

Detailed description

A retrospective and observational monocentric study fo six patients with DSAEK after prior penetrating keratoplasty (PK). The data collected are: demographic characteristics, ophthalmological comorbidities, initial indication of PK, delay between PK and DSAEK. Preoperative Visual Acuity and at 1, 3 and 6 months postoperative were collected in logmar for analysis. The central cornea and graft thickness measured in OCT as well as the postoperative complications were also collected.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* with endothelial decompensation after penetrating keratoplasty * surgery realised by the same surgeon

Exclusion criteria

* None

Design outcomes

Primary

Measure	Time frame	Description
visual acuity	change from visual acuity at 6 month	pre and postoperative visual acuity in logmar

Secondary

Measure	Time frame	Description
cornea thickness at 6 months	change from cornea thickness at 6 months	the central cornea and graft thickness measured in OCT
cornea thickness at 10 years	change from cornea thickness at 10 years	the central cornea and graft thickness measured in OCT
postoperative complications	month 6	all the postoperative complications were collected
visual acuity at 10 years	change from visual acuity at 10 years	pre and postoperative visual acuity in logmar

Outcome results