Sensitization to Legumes
Conditions
Brief summary
The Mediterranean diet is a model for health. Indeed, according to some epidemiological studies, it would participate in the prevention of various diseases such as cardiovascular diseases, diabetes type 2, cancer and obesity. Among the foods composing the Mediterranean diet, wheat and legumes are strongly represented. The introduction of legumes into an easily prepared and economical food for a large part of the population will lead to an increase in consumption. The combination of durum wheat semolina and legume flour would benefit from the nutritional qualities of the two raw materials (high protein, slow digestible carbohydrates, fiber, vitamins and minerals), but also of their double wheat-legume allergenicity.
Interventions
OTHERSkin prick tests with four native legumes
Skin prick tests with four native legumes
Sponsors
University Hospital, Montpellier
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SCREENING
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
2 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients seen in allergy consultation * The patient (or parents for the under 18 years) must have given their free consent and signed the consent chart * Men and women are included * The patient is at least 2 years old
Exclusion criteria
* The patient is pregnant * The patient is breast-feeding * The patient is unable to stop in antihistamine medication for at least 7 days * The patient refused or is unable to sign the consent chart * The patient has a dermographism
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Sensitization rate to four cooked legumes in the population consulting in Allergy Unit at the University Hospital of Montpellier | 10 minutes (the average duration of the test will not be significantly increased) | A prick test will be considered as positive in the presence of a wheal of urticaria of at least 3 mm in size |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Describe the population with positive skin prick tests to legumes | 5 years | A prick test will be considered as positive in the presence of a wheal of urticaria of at least 3 mm in size |
| Associations between symptoms on ingestion of these legumes | 5 years | Association between the positivity of the legume prick test and (1) symptoms upon ingestion of legumes (e.g., aracid and other fruits and vegetables), (2) symptoms of rhinitis, asthma, atopic eczema, and (3) positivity to other prick tests of the standard pneumallergen battery |
Countries
France
Outcome results
None listed