Myocardial Function of the Stenosis Aortic Valve Before and Beyond Valve Replacement
Conditions
Brief summary
Study the consequences on heart muscle of the stenosis aortic valve before and after the replacement procedure, the repercussion on heart. Study the impact on the heart of sick valve can affect on well-being and prognosis in the year following the surgery.
Interventions
PROCEDUREstenosis aortic valve
The exams to be realized : * a clinical examination with blood pressure * a 12-lead surface electrocardiogram * a standard biological assessment including NTproBNP (Brain Natriuretic Peptide) * Transthoracic echocardiography at baseline and 12 months after the aortic valve intervention on the (according to recommendations) * a cardiac MRI looking for fibrosis myocardial
Sponsors
Rennes University Hospital
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* major patient freely accepting to participate in the study * non-opposition signed * aortic surface \<1cm² or \<0.6cm² / m² of indication surgical restraint * oriented to short interventional management surgical term * LVEF Left ventricular ejection fraction\> 50% * In the subgroup MRI-fibrosis, absence of indication for performing MRI
Exclusion criteria
* patient under guardianship, curatorship or safeguard of justice * minor patient * pregnant woman * patient with significant polyvalvulopathy for which it is from the start programmed more than aortic valve replacement * patient with severe coronary artery disease requiring revascularization * allergy to the contrast product
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint is a composite endpoint: all-cause death, cardiovascular hospitalization: cardiac decompensation, atrial fibrillation within 12 months of surgical or percutaneous aortic valve replacement. | 1 day of inclusion |
Countries
France
Outcome results
None listed