Visual Outcomes Following Descemet Stripping Automated Endothelial Keratoplasty

Visual Outcomes Following Descemet Stripping Automated Endothelial Keratoplasty for Corneal Endothelial Dysfunction

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03685734

Acronym

VO-DSAEK

Enrollment

Registered

2018-09-26

Start date

2015-01-01

Completion date

2016-01-01

Last updated

2018-09-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Corneal Endothelial Disorder

Keywords

DSAEK

Brief summary

To assess objective and subjective visual outcomes achieved by patients with corneal endothelial dysfunction who have undergone surgical treatment with Descemet stripping automated endothelial keratoplasty (DSAEK).

Detailed description

Since 2006, the technique by removing the Descemet membrane from the recipient cornea was renamed Descemet stripping automated endothelial keratoplasty (DSAEK). In recent years, DSAEK techniques have evolved, favoring increasingly thinner and finer grafts, known as ultrathin DSAEK (UT DSAEK), with the aim of obtaining better visual results. Endothelial keratoplasty is now the most common surgical procedure used to treat endothelial dysfunction. The current study focused on assessing both objective and subjective visual quality outcomes following DSAEK.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Clinical eligibility for DSAEK * Informed written consent * Successful completion of DSAEK procedure * Postoperative follow-up at least 1 year * Ability to respond to the questionnaire

Exclusion criteria

* Patients with clinical edematous cornea * With significant stromal opacity * With major disturbances of ocular surface * Previous corneal surgery

Design outcomes

Primary

Measure	Time frame	Description
Visual acuity	1 year	Scored with reference to the logarithm of the minimum angle of resolution (logMAR) and its variation in line gain.

Outcome results