Cardiorenal Syndrome
Conditions
Keywords
cardiac surgery, venous congestion, diuretic depletion
Brief summary
Following cardiac surgery, right ventricular function may be altered leading to increase central venous pressure and decrease in renal blood flow. The investigator's standard care includes use of diuretic to avoid interstitial fluid accumulation. The aim of the study is to assess cardiac and renal function before and after depletion by using diuretics
Detailed description
The study will compare cardiac and renal data before and 6 hours after use of diuretic * Echocardiographic measure of right function (S wave, TAPSE, ventricle surfaces, inferior vena cava diameter) and left function (LVEF, cardiac output * Renal function: cumulative diuresis, creatinine level variation and incidence of acute kidney injury using KDIGO classification (creatinine level\>26.5 or diuresis\<0.05 ml kg-1 h-1)
Interventions
PROCEDUREdiuretic use
use of diuretic
Sponsors
Centre Hospitalier Universitaire, Amiens
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
patient undergoing elective cardiac surgery under cardiopulmonary bypass
Exclusion criteria
* heart transplantation * use of vasopressor * chronic renal disease (DGF under 30 ml min-1) * endocarditis * patient under ECLS or CPIA * patient under 18-year-old
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| change in renal glomerular filtration before and 6 hours after use of diurectic | at baseline (o hours) and 6 hours after use of diuretic | change in renal glomerular filtration before and 6 hours after use of diurectic |
Countries
France
Outcome results
None listed