Minor Troponin Elevations in Patients With Atrial Fibrillation

Etiology of Minor Troponin Elevations in Patients With Atrial Fibrillation Visiting Emergency Department

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03683836

Acronym

Tropo-AF

Enrollment

3394

Registered

2018-09-25

Start date

2016-06-01

Completion date

2023-10-30

Last updated

2024-05-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillation, Myocardial Ischemia

Brief summary

This study aims at identifying the etiology of troponin-T elevations in patients with atrial fibrillation visiting the emergency department.

Detailed description

The aim of this study is to identify the factors associated with minor cardiac troponin-T elevations in patients presenting in emergency department (ED) with atrial fibrillation (AF) diagnosis , and the possible implications it has on the patients prognosis. Data on 3394 patients from the Turku university hospital catchment area with diagnosis of AF on admission to ED and minor troponin-T elevation were analyzed. Patients were classified into three groups according to the troponin-T value: troponin \<15ng/l, 15-50ng/l and 51-100ng/l. Individual patient records were reviewed.

Interventions

DIAGNOSTIC_TESTNo intervention

No intervention

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* two troponin T tests within 72 hours of ED admission * Prior diagnosis of AF or AF at admission

Exclusion criteria

* Age \< 18 years

Design outcomes

Primary

Measure	Time frame	Description
All-cause mortality, myocardial infarction, ischemic stroke	12 months	Major adverse cardiac or cerebrovascular event within one year

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026