Infertility
Conditions
Brief summary
Despite constant progress in in vitro fertilization (IVF) techniques and ovarian stimulation, pregnancy and embryo implantation rates remain modest . The phenomenon of embryo implantation depends both on the embryo itself and on endometrial receptivity
Detailed description
A favorable uterine medium is necessary for embryo implantation, but endometrial receptivity can be negatively affected by ovarian stimulation . Study of endometrial receptivity is especially limited in the context of IVF cycles . Biopsy of the endometrium cannot be considered during the treatment, and this has encouraged the development and use of ultrasonography and Doppler-like non-invasive methods to evaluate ovarian response to the stimulation and uterine receptivity .
Interventions
DIAGNOSTIC_TESTTransvaginal US with Doppler study
Transvaginal Ultrasound with doppler study on endometrium will be made
Sponsors
Kasr El Aini Hospital
National Research Centre, Egypt
Aljazeera Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
\- Maternal age from 20 to 40 years. Women with BMI range from 20 - 35 Women diagnosed with primary infertility
Exclusion criteria
Maternal chronic medical disorder (diabetes mellitus or hypertension). Women diagnosed with autoimmune diseases or antiphospholipid syndrome
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The number of patients who will have positive pregnancy rate | within 2 months | patients who will get pregnant in ICSI cycle with measuring their doppler indices before ovum pick up |
Countries
Egypt
Contacts
Primary ContactMahmoud Alalfy
Outcome results
None listed