Bronchopulmonary Dysplasia, Prematurity, Very Low Birth Weight Infant
Conditions
Brief summary
The purpose of this study is to compare how premature infants who required oxygen for at least 28 days during their time in the NICU (Neonatal Intensive Care Unit) breathe at discharge compared to premature infants who did not require oxygen for at least 28 days during their time in the NICU.
Detailed description
Work of breathing tests will be performed on premature infants who required oxygen for at least 28 days during their time in NICU. These same work of breathing tests will be performed in another group of premature infants who did not require oxygen for at least 28 days during their time in the NICU. The two groups will be compared.
Interventions
OTHEREnrollment
All infants whose families consent will be enrolled and will all receive the same treatment which included measurements of work of breathing.
Sponsors
Christiana Care Health Services
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
1 Months to 7 Months
Healthy volunteers
Yes
Inclusion criteria
* Infants born at greater than 26 weeks gestation, weighing less than 1500 grams at birth. * Infants with diagnosis of BPD and without diagnosis of BPD
Exclusion criteria
* Infants with skeletal, neuromuscular, or abdominal surgical disorders that affect the accuracy of work of breathing measurements will be excluded.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Work of breathing indices | 25 minutes | Respiratory Inductance Plethysmography (RIP) measurements will be taken and Phase Angle will be measured. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Intermittent Hypoxia | 25 minutes | Oxygen saturation will be measured using a high resolution pulse oximeter. |
Countries
United States
Outcome results
None listed