Lung Diseases
Conditions
Keywords
Erector spinae plane block, Video-assisted thoracic surgery;, Intercostal nerve block, Patient-controlled intravenous analgesia
Brief summary
A randomized prospective trial to test the non-inferiority of erector spinae plane block (ESPB) in comparison with intercostal nerve block combined with patient-controlled intravenous analgesia in Thoracoscopic lung surgery
Detailed description
For patients undergoing thoracic surgery, postoperative pain greatly limited their recovery.Multimodal analgesia have shown good efficacy but without reaching full pain relief. The primary goal of this study is to observe the effect of ultrasound-guided erector spinae plane block in comparison with intercostal nerve block combined with patient-controlled intravenous analgesia in video assisted thoracic lung surgery.
Interventions
DRUGIntercostal Nerve Block with PCIA
Intercostal nerve block consists in the injection of Ropivacaine (4 ml,0.5%) in related intercostal spaces. Patient-controlled intravenous analgesia regimen is conducted with sufentanil.
Erector Spinae Plane Block consists in the injection of Ropivacaine (20ml, 0.5%), in the anatomical plane between the Erector Spinae muscles and transverse process, laterally to the spinous process of T5 . The catheter was inserted and secured in place under ecographic guidance, and a patient-controlled regional anesthesia regimen was conducted with 0.2% ropivacaine.
Sponsors
Peking University Third Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Patients to receive video assisted thoracoscopic lobectomy or bullectomy .
Exclusion criteria
* 1\. Patient refusal 2. Heavy skin eruption and infection at site of injection. 3. Coagulopathy. 4. Allergy to local anesthetics. 5. Taking analgesics.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pain score (NRS) | 4 hours from the end of procedure | Numeric Rating Scale is an 11-point scale used by doctors to evaluate patients' pain, where 0 is no pain and 10 the worst imaginable pain. For postoperative patients, an higher score shows inadequate analgesia and worse outcome. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pain score (NRS) | 8, 24,48 hours from the end of procedure | Numeric Rating Scale is an 11-point scale used by doctors to evaluate patients' pain, where 0 is no pain and 10 the worst imaginable pain. For postoperative patients, an higher score shows inadequate analgesia and worse outcome. |
| Analgesics consumption | During operation,4, 8, 24,48 hours from the end of procedure | Analgesics include opioids and nonsteroidal anti-inflammatory drugs |
| Incidence of side effects and complication during study | During operation,4, 8, 24,48 hours from the end of procedure | Side effects and complication |
Countries
China
Outcome results
None listed