Sleep Infra-slow Oscillations III

Sleep Infra-slow Oscillations III: an Observational Study in Healthy Subjects and Patients With Sleep Disorders With and Without Closed-loop Stimulation During Sleep

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03681327

Acronym

Sleep-ISO III

Enrollment

Registered

2018-09-24

Start date

2018-10-01

Completion date

2023-07-01

Last updated

2023-11-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Brief summary

In young healthy subjects, we will apply sensory stimuli at specific times during sleep to evaluate the probability that the stimulus evokes an arousal.

Interventions

OTHERSensory stimulation during sleep

Sensory stimulation during sleep

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

20 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* Willingness to participate and written informed consent * Aged 20 to 40 years at the time of screening * Body mass index (BMI) ≤ 30

Exclusion criteria

* Pregnancy or breast feeding at the time of screening * Sleep related breathing disorders * Any other sleep related breathing disorder according to AASM criteria * Current history of psychiatric disorders according to DSM-V * Current chronic treatment that may affect sleep * Any significant neurological disorder or other medical disease that may affect sleep * Any unstable medical condition * Any clinically significant sleep disorder

Design outcomes

Primary

Measure	Time frame	Description
Arousal probability	8 hours	Number stimuli that are followed by an EEG arousal divided by the total number of stimuli

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026