Recurrent Laryngeal Nerve Injuries, Thyroid Cancer
Conditions
Keywords
external branches of superior laryngeal nerve, thyroidectomy, thyroid cancer
Brief summary
The feasibility and effectiveness of Reversed Tracking Method for the identification and protection of extralaryngeal nerve branches in thyroid surgery were analyzed. Evidence-based medical evidence was used to evaluate the importance of EBSLN recognition and protection in thyroid surgery.
Detailed description
The incidence of thyroid cancer in the world is growing rapidly. The current incidence of thyroid cancer in China is about 4.2/100,000, ranking the fourth in the incidence of female malignant tumors. Surgical treatment is the first and most important treatment for thyroid cancer. According to the existing literature, the injury rate of EBSLN in thyroid surgery can be as high as 58%. The quality of sound changes caused by EBSLN injury affects the quality of life of patients after surgery, and even affects the work and career of patients. therefore, seeking better EBSLN protection The method has great social and economic benefits.
Interventions
PROCEDUREReversed Tracking Method
Reversed Tracking Method
Sponsors
Fujian Medical University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Intervention model description
Different methods of protection of external branches of superior laryngeal nerve
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
： 1. thyroid papillary cancer patients 2. thyroid adenoma patients 3. tumor diameter less than 4cm 4. patients who require only unilateral thyroid surgery as required by the guidelines
Exclusion criteria
1. The upper pole tumor invades the anterior dorsum and may accumulate the area of the superior laryngeal nerve; 2. Patients who have previously performed head and neck surgery; 3. Preoperative laryngoscopy and sound assessment abnormalities or previous vocal cord surgery history; 4. If there is a language or hearing impairment, the follow-up assessment cannot be completed; 5. The assessment failure of nerve function due to the technical deficiency of the IONM equipment Elimination criteria: 1. Patients with recurrent laryngeal nerve palsy after surgery affect the evaluation of the laryngeal nerve. 2. The patient is asked to withdraw from the follow-up assessment midway.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The identification rate of the external branch of the superior laryngeal nerve. | up to 6 months postoperatively | The identification rate of the external branch of the superior laryngeal nerve. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| videostrobolaryngoscopy | up to 6 months postoperatively | The voice assessment included pre- and postoperative videostrobolaryngoscopy and analysis of maximum phonation time (MPT), voice level (VL), fundamental frequency (Fo), and voice quality rating on GRBAS scale. |
| analysis of maximum phonation time (MPT) | up to 6 months postoperatively | The voice assessment included pre- and postoperative videostrobolaryngoscopy and analysis of maximum phonation time (MPT), voice level (VL), fundamental frequency (Fo), and voice quality rating on GRBAS scale. |
| Friedman classification | up to 6 months postoperatively | Anatomical variability of the external branch of the superior laryngeal nerve according to Friedman classification. |
| fundamental frequency (Fo) | up to 6 months postoperatively | The voice assessment included pre- and postoperative videostrobolaryngoscopy and analysis of maximum phonation time (MPT), voice level (VL), fundamental frequency (Fo), and voice quality rating on GRBAS scale. |
| voice quality rating on GRBAS scale | up to 6 months postoperatively | The voice assessment included pre- and postoperative videostrobolaryngoscopy and analysis of maximum phonation time (MPT), voice level (VL), fundamental frequency (Fo), and voice quality rating on GRBAS scale. |
| voice level (VL) | up to 6 months postoperatively | The voice assessment included pre- and postoperative videostrobolaryngoscopy and analysis of maximum phonation time (MPT), voice level (VL), fundamental frequency (Fo), and voice quality rating on GRBAS scale. |
Countries
China
Contacts
Primary ContactBo Wang, md
Outcome results
None listed