Cerebral Palsy
Conditions
Keywords
hip dislocation, GMFCS level 3,4,5
Brief summary
In children with cerebral palsy, secondary problems lead to hip dislocation. the purpose of this study is to find out the effects of botulinum toxin A on hip joint dislocation in cerebral palsy patients.
Detailed description
* Design: Prospective study * Inclusion criteria of patient group: who has a cerebral palsy and GMFCS level 3,4,5 * Intervention: applied medication Botulinum A injection (meditox 200unit) * Main outcome measures: The investigators will measure for finding evidence by checking the x-ray photograph, hip adductor and muscles pressure test and electromyography(EMG test) test of hip adductor, abductor and spine muscles.
Interventions
DRUGmedication Botulinum A injection.
In cerebral palsy patients, Botulinum toxin within the allowable dose of 16 U / kg per body weight will injected into both adductor longus, adductor magnus muscle at 3 U / kg, adductor brevis, and gracilis muscle at a dose of 1 U / kg.
Sponsors
Ju Seok Ryu
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
2 Years to 10 Years
Healthy volunteers
No
Inclusion criteria
* Severe cerebral palsy patients(GMFCS level 3,4,5) * 2 to 10 years old
Exclusion criteria
* Those who disagree with the study. * other than cerebral palsy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from hip adductor and spin muscles electromyography(EMG) test at a month | once at study, when patient enrolled and every once a month for one year | Use EMG to check the activity of the hip adductor and spine muscles of participants. This figures will give investigators a look at the association with a hip dislocation. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Whole spine AP and total Hip AP X-ray photograph | once at study, when patient enrolled and and after six month for one year | Whole spine and total Hip joint are checked with X-ray photograph. and investigators will check the progress of hip dislocation and spinal scoliosis. |
| hip adductor muscles pressure meter test | once at study, when patient enrolled and every once a month for one year | Pressures of hip adductors muscles are measured from pressure meter. and This figures will give investigators a look at the association with a hip dislocation. |
| Likert scale | once at study, when patient enrolled and every once a month for one year | Evaluate the satisfaction of botulinum toxin A injection. Likert scale is a response category that indicates the extent to which the question is for or against. Example) Very satisfied - normal - slightly dissatisfied - very dissatisfied |
| Hip and knee joint Range of motion(ROM) test | once at study, when patient enrolled and every once a month for one year | Measure the range of motion the knee and hip joints. |
| CPCHILD sacle | once at study, when patient enrolled and every once a month for one year | Evaluate the quality of life for patients with cerebral palsy. CPCHILD scale have 6section and each section measures scores by 0 to 5. |
Countries
South Korea
Outcome results
None listed