Inflammation Eye
Conditions
Keywords
vitrectomy, cryoindentation
Brief summary
Observational study, monocentric, prospective, descriptive and comparative (eye operated vs fellow eye).
Detailed description
After surgery by vitrectomy or preindentation, an anti-inflammatory treatment is conventionally prescribed for a duration of 1 month. However, frequently, during the post-operative control at one month, there may be signs of ocular inflammation or symptoms of discomfort justifying the prolongation of post-operative treatment. A 2012 study evaluated post-operative flare follow-up in 22 vitrectomized patients for retinal detachment, and showed a significantly higher flare 3 months after surgery, compared to the other eye and pre-surgery value. In this study, the investigators wish to study postoperative inflammation in patients operated for posterior segment ocular surgery (vitrectomy or preindentation) measured by laser flashmeter on a follow-up of one year.
Interventions
OTHERLaser Flare Meter
Measurement of the inflammation of the operated eye and the fellow eye before the surgery and at each post-surgery visit: D7, M1, M2, M3, M6, M12
Sponsors
Rennes University Hospital
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Major patient, * Operation of vitrectomy or preindentation in the ophthalmology department of Rennes University Hospital for one of the following reasons: * Retinal detachment, rhegmatogenous or not * Combined surgery * Membrane peeling * Macular hole * Optically targeted vitrectomy (Terson's syndrome, intravitreous haemorrhage) * Covered by a health insurance system, * Having received information on the protocol and not having expressed opposition to participating in the study
Exclusion criteria
* Vitrectomy for endophthalmitis or posterior uveitis, * Patient with vitreoretinal proliferation (grade B and C), * Pregnant or nursing woman, * Major patient subject to legal protection (safeguard of justice, guardianship, guardianship), person deprived of liberty.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Evolution of the flare value | Changes between baseline (preoperatively) and day 7, month 1, month 2, month 3, month 6, and month 12 measures | Evolution of the flare value preoperatively and then to D7, M1, M2, M3, M6, M12 of the operated eye |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Flare values of the fellow eye and the operated eye | Difference between flare values of the fellow eye and the operated eye at each evaluation time : baseline (preoperatively), day 7, month 1, month 2, month 3, month 6, and month 12 | Flare value of the fellow eye and the operated eye at each evaluation time |
Other
| Measure | Time frame | Description |
|---|---|---|
| Flare value of the operated eye | Changes between baseline (preoperatively) and day 7, month 1, month 2, month 3, month 6, and month 12 measures | Flare value of the operated eye preoperatively and at each evaluation time |
| Criteria associated with high inflammation | Baseline (preoperatively) | Identification of criteria associated with high inflammation : indication of surgery |
Contacts
Primary ContactDalal ASRI
Backup ContactCoralie DOUDNIKOFF
Outcome results
None listed