Thoracic Paravertebral Blocks
Conditions
Brief summary
The investigators designed a study to assess whether thoracic paravertebral blocks using a combination of ropivacaine and dexmedetomidine prolong nerve block duration.
Detailed description
The investigators designed a study to assess whether thoracic paravertebral blocks using a combination of ropivacaine and dexmedetomidine prolong nerve block duration. The effects of dexmedetomidine have only been compared at lower doses. This trial examined the effect of greater dose of dexmedetomidine on thoracic paravertebral block analgesia duration.
Interventions
DRUGDexmedetomidine
combination of ropivacaine and dexmedetomidine 20 ug every time
Sponsors
China Medical University, China
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
a single-dose thoracic paravertebral analgesia for postoperative pain control after thoracoscopic lobectomy
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Patients were included in the study if they were ethnic Chinese, * American Society of Anesthesiologists (ASA) physical status I or II, * candidates for general anesthesia undergoing thoracic surgery
Exclusion criteria
* Patients were excluded if they do not want to cooperate with the test, * had a history of radial artery puncture or coronary artery bypass grafting, * had acute vessel trauma,or had been diagnosed with Raynaud' disease, * had suffered from mental or neurological disorders
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change of analgesia duration | Change from Baseline to 3 days after surgery | Change of thoracic paravertebral block analgesia duration |
Countries
China
Outcome results
None listed