Depression, Insomnia
Conditions
Keywords
music, depression, sleep disturbances, insomnia, quality of life
Brief summary
Insomnia is a common sleep disorder for patients with depression. This has a major impact on the quality of life for the individual. The aim is to investigate, whether music intervention is effective in 1. improving sleep quality, 2. reducing symptoms of depression and 3. improving quality of life Participants use a sound pillow and selected music in the The Music Star app at home as a sleep aid in 4 weeks.
Detailed description
Depression is a common health problem in Denmark with a prevalence for depression of 17-18%. Depression has serious personal and social consequence. Sleep disorders are common in patients with depression. Resolving sleep disturbances in depression may prevent worsening of symptoms and relapse. Music listening is widely used as a sleep aid. A study from the Cochrane library shows consensus that music may be helpful to improve sleep quality in insomnia. It remains unclear if music listening is helpful to patients with depression as it is to a broader population. A randomized controlled trial address the use of music as a supplementary treatment to improve sleep in depression.
Interventions
OTHERMusic Intervention
Music intervention
Sponsors
Health Research Foundation
The Obel Family Foundation
Aase & Ejnar Danielsens Foundation
Aalborg University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Intervention model description
The study design is an explanatory mixed methods design in two parts. The first part is a two-arm parallel group, single center randomized controlled trial (n=120). Experimental group and waitlist control group receive standard treatment according to national guidelines. The experimental group use a sound pillow and The Music Star App at bedtime as a sleep aid in 4 weeks.The second part is an interview study (n=4). Qualitative data from a semi-structured interview on the use of music and sleep are used to discuss findings from the RCT.
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Out patients in treatment for depression in psychiatry, Unit for Depression, Aalborg University Hospital. * ICD-10 diagnosis of unipolar depression F32 or F33. * Sleeping problems identified by HAM-D by a total score of 3 on sleep items 4-6, or a single score = 2 on at least one sleep item. * Following treatment standards according to national guidelines.(pharmacological treatment, psychotherapy, psycho education, Electro Convulsive Therapy). * 4 weeks of treatment and/or in stabilized pharmacological treatment
Exclusion criteria
* ICD-10 diagnosis of depression F32 or F33 and psychotic episodes * substance or alcohol abuse * sentence to treatment by law * restless legs syndrome * obstructive sleep apnoea or other organic sleep disorders * hearing loss * dislike of music
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Sleep Quality - subjective | Change of sleep quality from baseline at 4 weeks | Questionnaire PSQI-DK on self reported sleep measuring subjective sleep quality, sleep latency, sleep duration, sleep disturbances, daytime dysfunctions and use of antidepressant agents |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Sleep Quality - subjective | Change of sleep quality from baseline at 8 weeks | Questionnaire PSQI-DK on self reported sleep measuring subjective sleep quality, sleep latency, sleep duration, sleep disturbances, daytime dysfunctions and use of antidepressant agents. |
| Sleep Quality - objective | Change of sleep quality from baseline at 4 weeks | Accelerometer Axivity Ax3 data logger carried as a hand wrist bracelet at night. A sleep analysis function by a generic algorithm provide data on sleep estimates. |
| Quality of life measuring subjective well-being | Change of quality of life from baseline at 4 weeks | The World Health Well-Being Index (WHO-5) |
| Quality of life measuring subjective psychological health, physical health, social relationships and environment. | Change of quality of life from baseline at 4 weeks | The World Health Organization Quality of Life (WHOQOL-Bref) |
| Symptoms of depression | Change of depression level from baseline at 4 weeks | The Hamilton Depression Rating Scale (HAM-D17). The scale consist of 17 items. Total score range is 0-52. Higher numbers represent more severe symptoms. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Duration of music intervention | 4 week music intervention period | log file data on duration of music intervention |
Countries
Denmark
Outcome results
None listed