Gingival Recession
Conditions
Keywords
clinical trial, root coverage, biomaterials, collagen matrix, coronally advanced flap
Brief summary
Coronally advanced flap plus connective tissue graft (CTG) is the gold standard therapy for root coverage. The bioabsorbable porcine collagen matrix (CM) has been widely used in periodontal and mucogingival surgery as a substitute for CTG and has achieved similar results. The CM has the advantage of no need of a second surgical area and availability overcoming the limitations of donor site in autograft. The aim of this study is to investigate the use of Mucoderm® in root coverage procedures combined with extended coronally positioned flap (ECAF), test group (TG), in comparison to the connective tissue graft associated with the ECAF, control group (CG).
Interventions
PROCEDURERoot coverage with collagen matrix graft
at one side, the root coverage have been done with a extended flap technique and collagen matrix graft. At the other side, the same technique was performed with connective graft.
PROCEDURERoot coverage with subepithelial connective tissue graft
at one side, the root coverage have been done with a extended flap technique and collagen matrix graft. At the other side, the same technique was performed with connective graft.
profilaxis, coronary polishing and scaling and root planning
Sponsors
University of Sao Paulo
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)
Masking description
The clinical parameters were screened by one single examiner that was not aware of the procedures
Intervention model description
Randomized Controlled Split-mouth clinical trial
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* CEJ without significant damage; * localized bilateral RT1 gingival recession ≥3 mm in the same arch
Exclusion criteria
* previous periodontal surgical treatment on the involved sites; * smokers * pregnants or lactating * compromised systemic health and contraindications for periodontal surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Root coverage after 6 months | 6 months | Root coverage is measured by the difference between the gingival recession height at 6 months and baseline |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Keratinized tissue gain after 6 months | 6months | The difference between keratinized tissue width and depth at 6 months and at baseline |
Countries
Brazil
Outcome results
None listed