High Sensitive CRP in Prediabetics and Diabetes

High Sensitive CRP Level in Prediabetics and Newly Diagnosed Type 2 Diabetic Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03673904

Enrollment

180

Registered

2018-09-17

Start date

2017-01-01

Completion date

2018-03-08

Last updated

2018-09-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Assess Level of High Sensitive CRP in Diabetics and Prediabetics

Brief summary

The aim of this study was to study the level of high-sensitivity CRP in sera of pre-diabetic and newly diagnosed patients with type 2 diabetes mellitus and its correlation with HOMA IR and HbA1c

Detailed description

This study will include (180) subjects, 60 pre-diabetic patients, 60 patients with newly diagnosed type 2 diabetes ( within one month of diagnosis) and 60 normal healthy non diabetic individuals as a control group. The study individuals will be recruited from the Diabetes and Internal Medicine Clinics of Fayoum University Hospital

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Inclusion criteria

* Pre-diabetic patients: * A fasting blood glucose level (100 to 125 mg/dL). or * A 2-hour blood glucose level (140 to 199 mg/dL) .or * Hb A1C 5.7% to 6.4%. * Newly diagnosed type 2 diabetes: (maximum within one month from diagnosis) * A fasting blood glucose level \>126 mg/dl * A 2-hour blood glucose level \> 200 mg/dl * Hb A1C \> 6.5%

Exclusion criteria

* Pregnant or lactating females. * Patients who have recent infection. * Patients with acute inflammatory diseases as autoimmune diseases. * Patients with malignancy or on chemotherapy. * Patients with acute or chronic liver or renal diseases

Design outcomes

Primary

Measure	Time frame
statistical significant elevation of high sensitive CRP in diabetics and prediabetes	2 years

Outcome results