Prevalence of a Localized or Diffuse Pruritus in a Population With One or Several, Primitive or Secondary, Brain Tumor(s)

Study on the Prevalence of a Localized or Diffuse Pruritus in a Population With One or Several, Primitive or Secondary, Brain Tumor(s)

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03673878

Acronym

PRURI-C

Enrollment

200

Registered

2018-09-17

Start date

2020-06-29

Completion date

2021-09-05

Last updated

2022-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain Tumor, Pruritus

Brief summary

The association between the presence of pruritus, especially centrofacial, and the presence of a brain tumor is a widespread notion in the medical community but based on a single publication by Andreev et al. in the British Journal of Dermatology published in 1975. No other study has studied this association with a rigorous methodology. The aim of this study is to evaluate the prevalence of pruritus in patients with one or more primary or secondary brain tumor(s), benign(s) or malignant(s).

Detailed description

* Monocentric prospective observational study * On the inclusion period * Patients who are seen in radiotherapy consultation and / or department of neurosurgery * Complying with the inclusion criteria, not falling within the exclusion criteria * Re-reading of cerebral MRI (cMRI) with precision on the location(s) of the brain tumor(s) according to a predefined anatomic descriptive diagram * Complete the questionnaire by a dermatologist (characteristics of pruritus, brain lesion(s), characteristics of the population)

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age \> 18 years * Diagnosis of benign or malignant brain tumor, primary or secondary. * Accepted non-opposition * Realization of a cerebral MRI (cMRI)

Exclusion criteria

* Age \< 18 years * Absence of cerebral imaging of the cMRI type * Absence of non opposition * Realization of a treatment modifying the brain structure (radiotherapy / surgery)

Design outcomes

Primary

Measure	Time frame	Description
Presence of itching for more than 1 week in a patient with one or more brain tumor(s), primary or secondary, benign(s) or malignant(s).	1 year	Presence of itching for more than 1 week in a patient with one or more brain tumor(s), primary or secondary, benign(s) or malignant(s).

Countries

France

Outcome results