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Comparison of Plant and Animal Proteins on Amino Acid Concentrations

Randomized Clinical Trial in Healthy Men Evaluating the Impact of Dairy and Plant-based Protein Blends on Plasma Amino Acids

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03673839
Enrollment
20
Registered
2018-09-17
Start date
2018-09-20
Completion date
2018-11-21
Last updated
2018-11-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Resistance-Trained Males

Brief summary

The study purpose is to assess various protein blends, which differ in protein quality, and the impact on blood amino acid response in male subjects.

Interventions

OTHERAnimal Proteins (crossover)

Animal proteins mixed with water and consumed as a beverage once by the subject in a 4x4 Williams square crossover design

OTHERPlant-based protein blends type 1 (crossover)

Plant-based protein blends mixed with water and consumed as a beverage once by the subject in a 4x4 Williams square crossover design

OTHERPlant-based protein blends type 2 (crossover)

Plant-based protein blends mixed with water and consumed as a beverage once by the subject in a 4x4 Williams square crossover design

OTHERPlant-based protein blends type 3 (crossover)

Plant-based protein blends mixed with water and consumed as a beverage once by the subject in a 4x4 Williams square crossover design

Sponsors

Danone North America
Lead SponsorINDUSTRY

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
MALE
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy, resistance-trained adult men 18-35 years of age, inclusive, at the screening visit. * BMI between 18.5 and 29.9 kg/m² inclusive at sceening * Self-reported resistance training experience of no less than two years , and have participated in resistance training of at least 1h two days per week for the past six months. * Willing to abstain from any protein supplements for 1 day prior to the study intervention phase (i.e. from the randomised visit, Visit 2)

Exclusion criteria

\-

Design outcomes

Primary

MeasureTime frameDescription
Plasma essential amino acids amounts4 hoursFollowing an overnight fast, blood amino acids will be measured over 4 hours

Secondary

MeasureTime frameDescription
Kinetic response of the branch chain amino acids4 hoursFollowing an overnight fast, plasma branch chain amino acids amounts (area under the curve) will be measured over 4 hours at fasting
Maximum amount of plasma branch chain amino acid amounts4 hoursThe maximum plasma branch chain amino acid amount will be measured over 4 hours

Other

MeasureTime frameDescription
Time to reach the maximum amount of plasma branch chain amino acid amounts4 hoursThe time to reach the maximum of plasma branch chain amino acid amount will be measured over 4 hours

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026