Internal Jugular Vein Distensibility and Pleth Variability Index(PVI) for Evaluating Fluid Responsiveness

Internal Jugular Vein Distensibility and Pleth Variability Index for Evaluating Fluid Responsiveness

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03673475

Enrollment

Registered

2018-09-17

Start date

2018-02-01

Completion date

2018-09-30

Last updated

2018-11-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intravascular Volume

Brief summary

Assessment of intravascular volume status is crucial in order to predict the efficacy of volume status in major abdominal surgery. The aim of the study is to verify the feasibility and usefulness of the internal jugular vein distensibility index as an adjunct to the pleth variebility index(PVI) to predict fluid responsiveness in major abdominal surgery.

Detailed description

Forty patients above age 18 and ASA status I-III who are undergoing major abdominal surgery will be enrolled in the study. patients with right heart failure, arrythmia, severe valve stenosis or regurgitation will be excluded. After induction of general anesthesia, when the patients are hemodynamically stabilised, PVI and jugular vein distensibility will be calculated and recorded. after volume load with 500 ml gel infusion(in 15 min), measurements will be repeated within 10 minutes and recorded. Patients will be allocated to 2 groups according to the change in mean arterial pressure(MAP) after volume expansion: Responders will be defined as an increase in MAP by \>%10; while nonresponders will be defined as an increase in MAP \<%10 or decrease in MAP.

Interventions

PROCEDUREAssessment of fluid responsiveness

assessment of intravascular volume status using pleth variebility index and internal jugular vein distensibility in major abdominal surgery

Study design

Observational model

OTHER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* American Society of Anesthesiologists(ASA) physical status I-III patients * patients undergoing major abdominal surgery

Exclusion criteria

* arrythmia * severe right ventricle failure

Design outcomes

Primary

Measure	Time frame	Description
number of patients with significant change in VJI distensibility and pleth variebility index	during surgery at day 0	volume responders with significant change in jugular vein distensibility and pleth variebility index

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026