Levels of High-Sensitivity C-Reactive Protein in Heart Transplant Patients

Levels of High-Sensitivity C-Reactive Protein in Heart Transplant Patients With and Without Periodontitis

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03671408

Enrollment

Registered

2018-09-14

Start date

2016-04-20

Completion date

2018-06-10

Last updated

2018-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart Transplant Failure, Periodontitis, Crp

Keywords

heart transplant, periodontitis, hsCRP

Brief summary

Objectives: The outcomes of heart transplantation are very favorable but inflammation still plays a critical role in deterioration of chronic transplants. Periodontal diseases are not only limited to supporting structures of the teeth, they also cause systemic inflammation. Based on the importance of inflammation in heart transplant recipients and the association between periodontal disease and systemic inflammation, this study explored whether periodontitis may be a modifier of serum high-sensitivity C-reactive protein (HsCRP) in heart transplant patients.

Interventions

OTHERclinical measurements

only clinical parameters were recorded

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

11 Years to 65 Years

Healthy volunteers

Inclusion criteria

be clinically stable be at least 1 year post-transplant; no history of antibiotic use during the preceding 4 months have had no periodontal treatment within the previous year.

Exclusion criteria

having other systemic infections

Design outcomes

Primary

Measure	Time frame	Description
hscrp levels	day 1	serum hscrp levels were compared between the groups

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026