Cardiovascular Diseases
Conditions
Keywords
risk score, risk management, NCDR, interventional cardiology
Brief summary
The validity and applicability of different clinical risk scoring models in a variety of settings of interventional cardiology is evaluated in a retrospective and continuing prospective single-center registry at University Hospital Düsseldorf. Risk-adapted safety interventions are additionally tested.
Detailed description
Beginning with a retrospective assessment of 2014-2017 and continuing with a prospective registry, clinical outcomes of interventional cardiac catheterization procedures at University Hospital Düsseldorf in a variety of settings (elective and emergency coronary procedures, structural and rhythmologic cardiac interventions etc.), will be evaluated. Different risk scoring models are recommended for risk stratification by cardiovascular societies (e.g. GRACE, CRUSADE, NCDR, ACEF, EUROScore scores) and will be evaluated for their applicability to contemporary and local clinical practice in interventional cardiology. Risk-adapted safety interventions (e.g. intensified monitoring, vascular access closure, renal protective measures) will be applied to all patients and will be evaluated for their impact on clinical outcomes.
Interventions
OTHERrisk score
risk score
Sponsors
Heinrich-Heine University, Duesseldorf
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* \>18 yeas of age, written informed consent, cardiac catheterization at university hospital Düsseldorf, Germany
Exclusion criteria
* no written informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| mortality | 30 days | In-hospital mortality will be assessed and primarily reported |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Long-term mortality | up to 5 years post procedure | long-term mortality up to five years post procedure will be assessed and report |
| Bleeding (according to BARC bleeding definition) | 30 days and up to 5 years post procedure | in-hospital and long-term minor and major bleeding up to five years post procedure will be assessed and reported |
| Acute and chronic kidney injury (according to KDIGO definitions) | 30 days and up to 5 years post procedure | in-hospital and long-term acute and chronic kidney injury up to five years post procedure will be assessed and reported |
| TIA and Stroke | 30 days and up to 5 years post procedure | in-hospital and long-term cerebrovascular events (TIA and stroke) up to five years post procedure will be assessed and reported |
| Quality of life (assessed by standardized QoL surveys) | 30 days and up to 5 years post procedure | in-hospital and long-term impact of interventional procedures on quality of life up to five years post procedure will be assessed and reported |
Countries
Germany
Outcome results
None listed