Dizziness
Conditions
Keywords
vestibular schwannoma, gammaknife radiosurgery, vestibular evaluation
Brief summary
Vestibular schwannoma is a benign tumor located on the vestibular nerve. Patient could present dizziness symptoms cause to the tumor, and at least after the treatment by gamaknife radiosurgery or microsurgery resection. Only few studies keep the interest about dizziness symptoms and treatment modality in vestibular schwannoma. In the study dizziness symptoms were compared before and after the treatment of vestibular schwannoma by radiosurgery gammaknife or microsurgery resection. 2 scales were used : dizziness handicap inventory (DHI) and dizziness functionnal scale (AAO).
Interventions
RADIATIONRadiosurgery gammaknife
This procedure use intense gamma ray, which are concentrated to the precise volume of the tumor that used to stop the progression of the tumor
PROCEDUREMicrosurgery resection
Classical surgical approach with oto-neurosurgery procedures
Sponsors
University Hospital, Grenoble
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patient treated of an one side vestibular schwannoma between 01/01/2012 and 31/12/2017, follow at the Grenoble University Hospital * treatment : gamaknife radiosurgery or microsurgery resection * no opposition of the patient
Exclusion criteria
* association of gamaknife radiosurgery and microsurgery resection * bilateral vestibular schwannoma
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Vestibular evaluation DHI | From 4 years to 6 months | The investigator use a standarised scale : \- Dizziness Handicap Inventory (DHI). This scale combines 25 questions with three answers for each proposition about dizzyness in daily life situation : everytime (quote 4), sometimes (quote 2), never (quote 0). The scores are summing to obtain a value on 100. The scale is completed before and after the treatement. The investigator send the scale to the patient by mail way. |
| Vestibular evaluation AAO | From 4 years to 6 months | The investigator use a standarised scale : \- Dizziness Functionnal Scale (AAO), this is a scale quote from 1 (no symptoms of dizzyness) to 6 (major disability). The patient have to choise only one item that correspond to the condition. The scale is completed before and after the treatement. The investigator send the scale to the patient by mail way. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Facial fonction | From 4 years to 6 months | House and Brackmann scale : This scale is a standarised assessment of facial fonction from grade I : normal ; to grade VI : total paralysis. Each scale is completed after the treatement. |
| Hearing function | From 4 years to 6 months | This information is based on a question to the patient about the usefulness of hearing prothesis. So there are 2 groups : useful hearing (normal hearing or used hearing prothesis) or useless hearing (unsused hearing prothesis) The information is completed before and after the treatement. |
| Tumor control | From 4 years to 6 months | Tumor control is based on MRI size description (in mm): So there are 2 groups : controled or evolution of the tumor. * for microsurgery resection group the investigator keeps interest about the remaining size * for radiosurgery gammaknife group the investigator keeps interest about the stability or the reduction of the tumor The result is completed after the treatement. |
Countries
France
Outcome results
None listed