Real World Assessment of Effects of Beta-blockers on Patients With Acute Coronary Syndrome

Real World Assessment of Effects of Beta-blockers on Patients With Acute Coronary

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03669991

Enrollment

2200

Registered

2018-09-13

Start date

2018-08-31

Completion date

2022-07-31

Last updated

2018-09-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Coronary Syndrome

Brief summary

The study is aimed to optimized the dose-adjusted regimen of beta-blockers in patients with acute coronary syndrome by investigating therapeutic and curative results of target doses Beta-blockers using the dose-adjusted pathway of beta-blockers.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 120 Years

Healthy volunteers

Inclusion criteria

* Age ≥ 18 years * Patients diagnosed as acute coronary syndromes including acute ST-segment elevation myocardial infarction (STEMI) and non-ST-segment elevated acute coronary syndrome (NSTE-ACS) * Patients or whose legal representatives signed written informed consent form

Exclusion criteria

Patients should been excluded if they meet any of the following

Design outcomes

Primary

Measure	Time frame	Description
Major adverse cardiovascular and cerebrovascular events (MACCE)	Within 1 year after surgery	MACCE were defined as a composite of all-cause death, myocardial infarction (MI), unplanned target vessel revascularization (TVR), stent thrombosis (ST) and stroke.

Secondary

Measure	Time frame	Description
Resting heart rate	Within 1 year after surgery	The resting heart rate of the body is the number of contractions of the heart that occur in a single minute while the body is at complete rest.
Blood pressure (systolic & diastolic)	Within 1 year after surgery	Blood pressure (BP) is the pressure of circulating blood on the walls of blood vessels.
Ejection fraction	Within 1 year after surgery	Ejection fraction (EF) is the volumetric fraction of fluid (usually blood) ejected from a chamber (usually the heart) with each contraction (or heartbeat).
Serum norepinephrine	Within 1 year after surgery	Norepinephrine is a neurotransmitter that is secreted in response to stress.

Countries

China

Contacts

Primary ContactMin Yang, MD

13810727489@163.com+86-10-88396173

Backup ContactKuo Zhang, MD

kzhang23@outlook.com+86-18813019602

Outcome results