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Clinical Research of H3F3AK27M in Spinal Glioma and Its Impact on TMZ Chemoradiotherapy

Clinical Research of the Molecular Phenotype Distribution of H3F3AK27M in Spinal Glioma and Its Impact on TMZ Chemoradiotherapy

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03668522
Enrollment
60
Registered
2018-09-12
Start date
2018-09-30
Completion date
2020-01-31
Last updated
2018-09-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal Tumor

Keywords

H3F3AK27M

Brief summary

H3F3AK27M may be a feature of primary spinal cord glioma and affect the outcome and prognosis of TMZ chemoradiotherapy.

Interventions

OTHERGenetic testing

To determine whether H3F3AK27M exist in spinal glioma

Sponsors

Southern Medical University, China
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Surgical treatment and pathological confirmation of spinal glioma in our department and is the first case without any treatment before operation.

Exclusion criteria

* The tumor is recurrent or has been treated before operation.

Design outcomes

Primary

MeasureTime frameDescription
positivethrough study completion, an average of 1 yearpositive of H3F3AK27M

Countries

China

Contacts

Primary ContactLu Yuntao, M.D., Ph.D
lllu2000@163.com13632101002

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026