Surgical Anastomosis
Conditions
Keywords
anastomotic perfusion, tissue oxygen saturation
Brief summary
In this study, gastrointestinal anastomoses are examined with a hyperspectral camera.
Detailed description
The anastomoses were examined under standardized conditions directly after creation. The measurements were performed like described before, using the TIVITA Tissue system (Diaspective Vision GmbH, Am Salzhaff, Germany). This HSI-camera provides hyperspectral images with a high spectral resolution (5 nm) in the visible and near infrared range (500-1000 nm). The distance between camera and object was 30 cm for all measurements. The Number of Effective Pixels at this distance is 640 × 480 (x-, y-axis. The resulting field of view (FOV) has the dimensions 6.4 × 4.8 cm2 and a spatial resolution of 0.1 mm/pixel. The FOV is illuminated by 8 halogen spots (20 W each). The ceiling lights and other light sources were switched off, to avoid artifacts during the measurement (approximately 10 seconds). A RGB image and 4 false color images that represent physiologic parameters are intraoperatively provided by an analysis software. This work is focused on tissue oxygenation (StO2), which represents the relative blood oxygenation in the microcirculation of superficial tissue layers (approximately 1 mm) and the near-infrared (NIR) Perfusion Index, representing tissue layers in 4-6 mm penetration depth.
Interventions
PROCEDUREHyperspectral Imaging
Photos were taken with the hyperspectral camera of the gastrointestinal anastomosis.
Sponsors
University of Leipzig
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* all gastrointestinal anastomoses
Exclusion criteria
* inability to consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Anastomotic Perfusion: (Oxygenation (StO2) | direct during the Operation (ca. 15-20 Minutes) | Oxygenation (StO2) in %: Relative O2 saturation of the blood immicrocircular system in superficial tissue layers (penetration depth: approx. 1 mm) |
| Anastomotic Perfusion: Tissue-Hemoglobin index | direct during the Operation (ca. 15-20 Minutes) | Tissue Hemoglobin index in %: Existing hemoglobin distribution in the microcircular system of the tissue area under consideration (index value) |
| Anastomotic Perfusion: Near Infrared Perfusion Index | direct during the Operation (ca. 15-20 Minutes) | Near Infrared Perfusion Index in %: Relative O2 saturation of the blood immicrocircular system in deeper tissue layers (penetration depth: 4-6mm; index value) |
| Anastomotic Perfusion: Tissue-Water-Index | direct during the Operation (ca. 15-20 Minutes) | Tissue-Water-Index in %: Existing water distribution in the tissue area under consideration (index value) |
Countries
Germany
Contacts
Primary ContactBoris Jansen-Winkeln, Dr.
Backup ContactInes Gockel, Prof. Dr.
Outcome results
None listed