Affective Disorders, Psychotic Disorder
Conditions
Keywords
PMR, anxiety, psychotic syndrome, quality of life
Brief summary
This study applied a randomized parallel case-controlled design. The study purpose was to evaluate the effects of progressive muscle relaxation on anxiety, psychiatric symptoms and quality of life among patients with chronic schizophrenia compared with an active control.
Detailed description
Background: Anti-psychotic drugs are limited in their ability to improve psychiatric symptoms, quality of life, and anxiety status in patients with chronic schizophrenia. Progressive Muscle Relaxation (PMR) can potentially reduce anxiety status and improve subjective welling in acute patients. It is an ideal rehabilitation intervention for patients with chronic schizophrenia. However, no study has investigated the effects of PMR on outcomes among patients with chronic schizophrenia. Design: This study applied a randomized parallel case-controlled design. Methods: Hospital-based randomized control trial in Taiwan. Eighty subjects with chronic schizophrenia were recruited from a psychotic ward and randomized into PMR, or control groups. Patients in the intervention group participated in progressive muscle relaxation for 12 weeks; while patients in the control group members received supportive treatment-as-usual (TAU). All participants completed anxiety, psychotic syndromes and quality of life measures at baseline, 3-month, and 3-month follow-up.
Interventions
BEHAVIORALprogressive muscle relaxation
intervention group: The experimental group received muscle relaxation training once a week for 3 consecutive months. The results were measured and followed up after 3 months.
Sponsors
Taipei Medical University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Outcomes Assessor)
Masking description
The rater did not know what interventions the participants belonged to.
Intervention model description
This study applied a randomized parallel case-controlled design. Hospital-based randomized control trial . Subjects were chronic schizophrenia who were recruited from a psychotic ward complex and randomized into PMR, or control groups.
Eligibility
Sex/Gender
ALL
Age
20 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Clinical diagnosis of Schizophrenia * Without the risk of self-injury and violence * Patients aged from 20-65 years old * Had no alcohol and drug abuse * Can use Mandarin or Taiwanese to communicate
Exclusion criteria
* Patients with another psychiatric comorbidity * Patients with musculoskeletal problems * patients who cannot sit last for 50 minutes * Had received progressive muscle relaxation training within the last year * Diagnosis of confirmed cardiovascular disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Quality of life simplified Chinese versions of the WHOQOL-BREF questionnaire were used | Measuring changes in quality of life from baseline to 6 months. | a 28-item questionnaire rated on a five-point Likert scale with four domains measuring: psychological health, physical health, social relationships and environment.so that higher scores refer to high QOL. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Anxiety Scale | measured at baseline, 3-month, and 3-month follow-up | State anxiety was assessed by the State anxiety inventory (SAI) of Spielberg (1984). The range of possible total scores is 20-80. Higher scores indicate higher levels of anxiety. |
| Positive and Negative Syndrome Scale (PANSS) | measured at baseline, 3-month, and 3-month follow-up | The instrument was developed by Kay et al. (1987) to assess psychopathology of schizophrenia which includes: positive, negative, general psychopathology symptoms. |
Outcome results
None listed