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Magnetic Nanoparticle Sperm Separation for Teratozoospermia Male and Women Older Than 35 Years

Magnetic Nanoparticle Sperm Separation for ICSI Cycles With Teratozoospermia and Over 35 Years Old Women Age

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03666364
Enrollment
1400
Registered
2018-09-11
Start date
2018-09-17
Completion date
2019-10-01
Last updated
2019-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Brief summary

Women over 35 years old are likely to suffer from impaired oocyte repair capacity. Teratozoospermia is a condition reflects morphological affection of sperm. These spermatozoa would add an extra burden on the oocyte after ICSI. Whether selecting mature sperm by magnetic nanoparticle protocol would provide a more competent sperm to a likely affected oocyte would improve ICSI outcomes is the question of this research.

Interventions

OTHERSperm preparation for ICSI

A new protocol for sperm preparation for ICSI cycles with teratozoospermia in over 35 years old women

Sponsors

Banon IVF Center Assiut, Egypt
CollaboratorOTHER
Ibn Sina Hospital
Lead SponsorOTHER_GOV

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender
FEMALE
Age
35 Years to 42 Years
Healthy volunteers
No

Inclusion criteria

* women indicated for ICSI but with teratozoospermia

Exclusion criteria

* Women not failing in this group

Design outcomes

Primary

MeasureTime frame
Ongoing pregnancy rateTwelve weeks of gestation

Secondary

MeasureTime frame
Embryo development after ICSISix days of culture

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026