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Patient Portal - Flu Reminder Recall

Improving Influenza Vaccination Delivery Across a Health System by the Electronic Health Records Patient Portal

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03666026
Enrollment
164205
Registered
2018-09-11
Start date
2018-10-02
Completion date
2019-04-02
Last updated
2021-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Influenza, Respiratory Tract Infections, Vaccines

Keywords

Reminder Recall (R/R), Influenza Vaccine, Electronic Health Record

Brief summary

This trial is taking place in Los Angeles, CA at clinics within the UCLA Health System. Despite the Advisory Committee on Immunization Practices (ACIP) recommendation in 2010 that all people above 6 months of age should receive an annual flu vaccine, vaccination rates remain low: at 6m-4.9 yrs. (70%), 5-17.9 yrs. (56%), 18-64.9 yrs. (38%), and \>65 yrs. (63%). The investigators will assess the effectiveness and cost-effectiveness of 1, 2, 3 MyChart R/R messages as compared to the standard of care control (no messages).

Detailed description

Annual epidemics of influenza cause substantial morbidity in the U.S. with up to 40,000 deaths/year and many hospitalizations, emergency and outpatient visits, and significant costs. Concerns about pandemic influenza elevate the need to prevent flu outbreaks. Numerous studies, including Cochrane or systematic reviews, and reports by the CDC and the Task Force on Community Preventive Services, highlight 4 evidence-based strategies to raise child and adult influenza vaccination rates: 1) increase patient demand by reminder-recall or education, 2) expand patient access to influenza vaccinations (e.g., flu vaccine clinics), 3) implement provider strategies such as prompts or standing orders, and 4) use societal strategies (e.g., reducing costs). Reminder/recall (R/R), sent by phone, mail or other modality, can improve child and adult influenza vaccination rates. However, fewer than one-fifth of pediatric or adult primary care practices utilize patient R/R. Barriers are lack of finances, personnel, and algorithms to identify eligible patients. A technological breakthrough that might overcome these barriers involves patient portals-- secure, web-based communication systems, embedded within electronic health records (EHRs), for patients and providers to communicate with each other via email and the internet. Portals are used by about half of Americans and half of UCLA patients. Portals can theoretically improve upon phone, mail or text R/R by adding information such as web links, videos, or images, allowing patients to schedule their own visits, and linking to the medical chart to customize messages. For this randomized control trial, the intent is to evaluate the impact of patient portal (MyChart) reminder recalls - either 1, 2, or 3 reminders versus the standard of care control group, specifically in relation to raising influenza vaccination rates among UCLA Health System's primary care patients aged 6 months and older. The proposed design of this 4-arm RCT: 1. Standard of care control (no messages) 2. Up to 1 portal R/R messages 3. Up to 2 portal R/R messages 4. Up to 3 portal R/R messages Hypothesis 1: \>1 portal R/R will increase vaccination rates vs. no R/R. Hypothesis 2: More R/R messages will raise vaccination rates (3R/R \> 2R/R \> 1R/R \> 0R/R). For the primary analysis, only the data from the randomly selected index patients (1 index patient per household) will be included. For relevant study arms, the first R/R message will be sent in October 2018.

Interventions

BEHAVIORAL1 MyChart R/R

Up to 1 flu vaccine reminder recall notice sent via MyChart to patients who are due for the flu vaccine, per the EMR records of the health system.

BEHAVIORAL2 MyChart R/R

Up to 2 flu vaccine reminder recall notices sent every 3-4 weeks via MyChart to patients who are due for the flu vaccine, per the EMR records of the health system.

BEHAVIORAL3 MyChart R/R

Up to 3 flu vaccine reminder recall notices sent every 3-4 weeks via MyChart to patients who are due for the flu vaccine, per the EMR records of the health system.

Sponsors

National Institute of Allergy and Infectious Diseases (NIAID)
CollaboratorNIH
University of California, Los Angeles
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
4 Months to No maximum
Healthy volunteers
No

Inclusion criteria

• A patient within the UCLA Health System identified by the system as a primary care patient per an internal algorithm, with a documented primary care visit within the last 3 years as of 8/1/18.

Exclusion criteria

• A patient not identified by the UCLA Health System's internal algorithm as a primary care patient.

Design outcomes

Primary

MeasureTime frameDescription
1.Receipt of the Annual Influenza Vaccine (Between 10/1/18 - 4/2/19) Among Index Patients. Outcomes Will be Assessed Via Vaccine Data Extraction From the Electronic Health Record and External Claims and Pharmacy Data.October 1, 2018 to April 2, 2019 during influenza vaccination seasonNumber of participants in each arm who received influenza vaccination

Countries

United States

Participant flow

Participants by arm

ArmCount
Standard of Care Control
Participants in this group will not receive any MyChart influenza vaccination reminders
41,070
1 MyChart R/R
Participants in this group will receive up to 1 influenza reminder recall notice via their MyChart account 1 MyChart R/R: Up to 1 flu vaccine reminder recall notice sent via MyChart to patients who are due for the flu vaccine, per the EMR records of the health system.
41,055
2 MyChart R/R
Participants in this group will receive up to 2 influenza reminder recall notices via their MyChart account 2 MyChart R/R: Up to 2 flu vaccine reminder recall notices sent every 3-4 weeks via MyChart to patients who are due for the flu vaccine, per the EMR records of the health system.
41,046
3 MyChart R/R
Participants in this group will receive up to 3 influenza reminder recall notices via their MyChart account 3 MyChart R/R: Up to 3 flu vaccine reminder recall notices sent every 3-4 weeks via MyChart to patients who are due for the flu vaccine, per the EMR records of the health system.
41,034
Total164,205

Baseline characteristics

CharacteristicStandard of Care Control3 MyChart R/RTotal2 MyChart R/R1 MyChart R/R
Age, Customized
0.5-17 years 0-5 years
7.4 Percent of participants7.4 Percent of participants7.4 Percent of participants7.3 Percent of participants7.3 Percent of participants
Age, Customized
18-64 years
73.8 Percent of participants74.0 Percent of participants74.0 Percent of participants74.1 Percent of participants73.9 Percent of participants
Age, Customized
>= 65 years
18.8 Percent of participants18.5 Percent of participants18.7 Percent of participants18.6 Percent of participants18.8 Percent of participants
Race/Ethnicity, Customized
Asian
10.1 Percent of participants10.3 Percent of participants10.3 Percent of participants10.3 Percent of participants10.4 Percent of participants
Race/Ethnicity, Customized
Black
4.4 Percent of participants4.8 Percent of participants4.6 Percent of participants4.7 Percent of participants4.6 Percent of participants
Race/Ethnicity, Customized
Hispanic Ethnicity
46.9 Percent of participants47.0 Percent of participants46.9 Percent of participants46.7 Percent of participants46.7 Percent of participants
Race/Ethnicity, Customized
Unkown
28.2 Percent of participants27.9 Percent of participants27.8 Percent of participants27.7 Percent of participants27.6 Percent of participants
Race/Ethnicity, Customized
White
57.3 Percent of participants57.1 Percent of participants57.3 Percent of participants57.2 Percent of participants57.5 Percent of participants
Received influenza vaccination in prior two years46.9 Percent of participants47.0 Percent of participants46.9 Percent of participants46.7 Percent of participants46.7 Percent of participants
Sex: Female, Male
Female
23985 Participants23964 Participants95773 Participants23889 Participants23935 Participants
Sex: Female, Male
Male
17085 Participants17070 Participants68432 Participants17157 Participants17120 Participants

Adverse events

Event typeEG000
affected / at risk
EG001
affected / at risk
EG002
affected / at risk
EG003
affected / at risk
deaths
Total, all-cause mortality
0 / 00 / 00 / 00 / 0
other
Total, other adverse events
0 / 00 / 00 / 00 / 0
serious
Total, serious adverse events
0 / 00 / 00 / 00 / 0

Outcome results

Primary

1.Receipt of the Annual Influenza Vaccine (Between 10/1/18 - 4/2/19) Among Index Patients. Outcomes Will be Assessed Via Vaccine Data Extraction From the Electronic Health Record and External Claims and Pharmacy Data.

Number of participants in each arm who received influenza vaccination

Time frame: October 1, 2018 to April 2, 2019 during influenza vaccination season

ArmMeasureValue (COUNT_OF_PARTICIPANTS)
Standard of Care Control1.Receipt of the Annual Influenza Vaccine (Between 10/1/18 - 4/2/19) Among Index Patients. Outcomes Will be Assessed Via Vaccine Data Extraction From the Electronic Health Record and External Claims and Pharmacy Data.15385 Participants
1 MyChart R/R1.Receipt of the Annual Influenza Vaccine (Between 10/1/18 - 4/2/19) Among Index Patients. Outcomes Will be Assessed Via Vaccine Data Extraction From the Electronic Health Record and External Claims and Pharmacy Data.15604 Participants
2 MyChart R/R1.Receipt of the Annual Influenza Vaccine (Between 10/1/18 - 4/2/19) Among Index Patients. Outcomes Will be Assessed Via Vaccine Data Extraction From the Electronic Health Record and External Claims and Pharmacy Data.15660 Participants
3 MyChart R/R1.Receipt of the Annual Influenza Vaccine (Between 10/1/18 - 4/2/19) Among Index Patients. Outcomes Will be Assessed Via Vaccine Data Extraction From the Electronic Health Record and External Claims and Pharmacy Data.15673 Participants
95% CI: [1, 1.03]
95% CI: [1, 1.04]
95% CI: [1, 1.04]

Source: ClinicalTrials.gov · Data processed: Feb 18, 2026