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The Evaluation of the Deepithelialized Gingival Graft Healing

Evaluation of the Effects of Different Fixation Methods on Wound Healing After Deepithelialized Gingival Graft

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03665272
Enrollment
40
Registered
2018-09-11
Start date
2018-01-10
Completion date
2018-09-03
Last updated
2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Wound Heal

Brief summary

The aim of this study was to compare of the effects of different fixation methods on deepithelialized gingival graft wound healing. Laser doppler flowmetry method was used to determine for blood perfusion changes. 40 patients were devided into two groups randomly and deepithelialized gingival graft procedure was performed and healings were evaluated by laser doppler flowmetry.

Detailed description

This study evaluates the effects of different fixation methods on the early healing period of deepithelialized gingival grafts placed for non-root coverage gingival augmentation by laser Doppler flowmetry Forty patients were assigned to study groups: 1)test : tissue adhesive or 2) control group: suture. Forty patients completed the study. Blood perfusion in the recipient site was measured by laser doppler flowmetry on the day of surgery and at 3 and 7 days after surgery. Quality of life and pain at recipient sites were also investigated.

Interventions

PROCEDUREdeepithelialized gingival graft fixation

one group's deepithelialized gingival graft fixed by sutures and other one's by tissue adhesive.

Sponsors

TC Erciyes University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* 18 to 65 years of age * systemically healthy * inadequate amount or absence of keratinized gingiva on the labial side of the lower incisor region * no restorations on the lower incisor region * no mucogingival surgical history in the lower incisor region * no periodontal treatment within the previous year * no systemic antibiotics taken for 6 months before the study * not pregnant or lactating * no-smoking

Exclusion criteria

* lower 18 and upper than 65 years of age * systemical disease * adequate amount of keratinized gingiva on the labial side of the lower incisor region * restorations on the lower incisor region * mucogingival surgical history in the lower incisor region * periodontal treatment within the previous year * systemic antibiotics taken for ‡6months before the study * pregnancy or lactating * smoking history or current smokers

Design outcomes

Primary

MeasureTime frameDescription
deepithelialized gingival graft blood perfusion changemeasurements were performed at the day of surgery, 1, 3 and 7 days.Blood perfusions (units) were measured by laser doppler flowmetry

Secondary

MeasureTime frameDescription
Deepithelialized gingival graft recipient bed pain changesmeasurements were performed at 1, 3 and 7 days post surgery.In this evaluations, we did not evaluate the total range we used subscale pain evaluation by visual analog scale. visual analog scale consisted of 10 units,in combination with a graphic rating scale.On the visual analog scale,the left and right end of the graphic represented the absence of pain (minimum 0)(score 0) and the most severe pain (maximum 10) (score 10),respectively. Patients were warned to complete the visual analog scale taking into consideration the intensity of their pain in the previous 24 hours on all recall days

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026