Laser-assisted ICSI Versus Conventional ICSI

Laser-assisted ICSI Effect on Degeneration Rate After ICSI

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03665103

Enrollment

966

Registered

2018-09-11

Start date

2018-09-17

Completion date

2019-08-05

Last updated

2019-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Brief summary

Degeneration rate after ICSI is expectable but decreasing it is a goal. Laser-assisted ICSI can serve to decrease this degeneration rate.

Interventions

OTHERLaser-assisted ICSI

Laser opening of the zona pellucida.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 40 Years

Healthy volunteers

Inclusion criteria

* all ICSI cycles

Exclusion criteria

* no exclusion

Design outcomes

Primary

Measure	Time frame
oocyte survival after injection	6 days of culture

Secondary

Measure	Time frame
blastocyst formation rate	6 days of culture
embryo utilization rate	6 days of culture
clinical pregnancy rate	four weeks after embryo transfer
ongoing pregnancy rate	Twelve weeks of gestation

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 18, 2026