Long Term Outcome Study in Patients With Pituitary Disorders

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03665064

Enrollment

1500

Registered

2018-09-11

Start date

2000-01-01

Completion date

2026-12-31

Last updated

2026-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pituitary Diseases, Pituitary Neoplasms

Keywords

Pituitary tumor, Acromegaly, Cushing, Prolactinoma

Brief summary

To determine the outcomes of patients with different pituitary disorders whether they are managed medically, surgically or expectantly.

Detailed description

A chart audit of around 1500 patients seen in two specific clinics, the Medical Pituitary Clinic and the combined Endocrine/Neurosurgical Pituitary Clinic at the University of Alberta Hospital, will be performed to determine the effectiveness of various treatment strategies on the long term outcome of specific pituitary disorders. The investigator's will collect retrospective demographic (age, sex, ethnicity), clinical (mode of presentation, hormonal parameters) and therapeutic outcome (surgical, medical, expectant and / or radiation treatment; co-morbidities and complications) of patients seen in these two clinics between January 2000 and December 2020.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* patients with confirmed pituitary disease

Exclusion criteria

* patients who do not have confirmed pituitary disease

Design outcomes

Primary

Measure	Time frame	Description
Progression free survival after pituitary surgery	up to 17 years post surgery	Using clinical, biochemical and imaging studies of a cohort of surgically operated patients to identify prognostic factors of tumor recurrence

Outcome results