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Treatment for Reading and Writing Deficits Following Acquired Brain Injury

Treatment for Reading and Writing Deficits Following Acquired Brain Injury

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03662243
Enrollment
2
Registered
2018-09-07
Start date
2018-08-30
Completion date
2020-09-15
Last updated
2021-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acquired Brain Injury, Agraphia, Alexia

Brief summary

Many people with acquired brain injuries have deficits in reading decoding, reading comprehension, and written expression. Alexia is a phenomenon in which a person who previously could read has trouble doing so after having sustained a brain injury; likewise, agraphia is an acquired writing problem affecting one or more aspects of written communication. Alexia and agraphia sometimes co-occur with one another and/or with other language challenges, but they can also occur as isolated phenomena. Methods to treat alexia and agraphia often focus on single intervention techniques that address aspects of reading or writing in isolation-such as matching written and spoken letters or letter sounds, performing choral reading, tracing letters, etc. Existing research suggests that the effectiveness of these techniques is limited. However, when used in combination, such techniques may promote improved reading and written communication skills. As such, the purpose of this research is to determine the extent to which a multicomponent intervention program improves the reading and writing capabilities of people with acquired alexia and/or agraphia.

Interventions

BEHAVIORALMulticomponent reading and writing treatment

Intervention procedures incorporated into the program include drilling on sight words to improve immediate recognition of common words; engaging in Multiple Oral Reading procedures to increase reading fluency; practicing oral spelling of sight words to improve spelling accuracy; generating written sentences to improve accurate spelling and use of written conventions (e.g., punctuation, capitalization); and summarizing and subsequently writing sentences about read material to establish strategies to enhance reading comprehension and promote written expression.

Sponsors

Quality Living, Inc.
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
14 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

* Survivor of acquired brain injury * Exhibits alexia and/or agraphia * Past or current client of Quality Living, Inc., Omaha, Nebraska * Fluent speaker of English

Exclusion criteria

* Vision impairment prohibiting reading of 24-point text * Auditory comprehension problems precluding understanding of consent/assent information

Design outcomes

Primary

MeasureTime frameDescription
Change in score on Test of Silent Reading Speed and Efficiency.Change from baseline at 8 weeksRaw scores range from 0 to 70, with higher scores indicating better performance.
Change in score on Word Attack subtest of the Woodcock-Johnson III Test of Achievement.Change from baseline at 8 weeksSubtest raw sores range from 0 to 32,with higher scores indicating better performance.
Change in score on Passage Comprehension subtest of the Woodcock-Johnson III Test of Achievement.Change from baseline at 8 weeksSubtest raw scores range from 0 to 47, with higher scores indicating better performance.
Change in score on Word Reading subtest of the Wide Range Achievement Test 4.Change from baseline at 8 weeksSubtest raw scores range from 0 to 70, with higher scores indicating better performance.
Change in score on Spelling subtest of the Wide Range Achievement Test 4.Change from baseline at 8 weeksSubtest raw scores range from 0 to 57, with higher scores indicating better performance.

Secondary

MeasureTime frameDescription
Oral reading rate of passagesAs the first of five tasks of each session for 8 weeks (each session is 1 hour).Words per minute (wpm) during independent oral reading of passages. The criteria for progression to subsequent passages is a reading rate of 80wpm or better.
Decoding errors during oral reading of passagesAs the first of five tasks of each session for 8 weeks (each session is 1 hour).Percent of uncorrected word decoding errors in a specified passage. The criterion for progression to subsequent passages is fewer than 5% uncorrected words production errors.
Oral spelling of wordsAs the second of five tasks of each session for 8 weeks (each session is 1 hour).Number of words spelled correctly on lists containing 15 words each. Introduction of a new word list will occur only after a participant correctly spells all words on the current list.
Sight word decoding accuracyOne time per week for 8 weeksPercent of correct decoding on 315 words included in Dolch pre-primer, primer, kindergarten, first grade, second grade, third grade, and nouns lists. Each word is scored as correct or incorrect, and a percent correct score is computed based on this scoring.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026