Incidence and Severity of Acute Respiratory Distress Syndrome (ARDS) in the French Wounded Soldiers

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03662230

Acronym

SDRA-OPEX

Enrollment

100

Registered

2018-09-07

Start date

2018-06-01

Completion date

2019-11-07

Last updated

2020-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Respiratory Distress Syndrome

Keywords

war wounds, intensive care unit

Brief summary

The purpose of this study is to evaluate the incidence of the ARDS in the French wounded soldiers.

Detailed description

The Acute Respiratory Distress Syndrome (ARDS) complicates war wounds. Among the repatriated wounded persons, it can appear in the first 7 days. It has been well described among American soldiers and it is known that it's serious, frequent and multifactorial. However, not a single study has described the frequency and the severity of the ARDS in French wounded soldiers. Thus the purpose of this study is to estimate the incidence and severity of the ARDS among the French wounded soldiers, admitted in continuing care and intensive care unit between 2001 and 2017. The analysis of this data collection will let us improve the medical care of the ARDS in Outside Operation.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patient evacuated from the theatre of outside operation and hospitalized in intensive care unit in France between 2001 et 2017

Exclusion criteria

* Opposition to the use of personal data

Design outcomes

Primary

Measure	Time frame	Description
Incidence of ARDS	Day 7	The appearance of ARDS is defined by a ratio of partial pressure arterial oxygen (PaO2) and fraction of inspired oxygen (FiO2) lower than 300 in 7 days after the wound.

Secondary

Measure	Time frame	Description
Assess the severity of ARDS	7 days	the severity of ARDS will be assessed regarding the necessity or not of non-invasive and invasive ventilation
Description of the severity of ARDS	7 days	the therapeutic intensity will be describe with : Maximal Positive end-expiration pressure (PEEP), curarisation, nitrogen monoxide (NO), prone position , Extracorporeal membrane oxygenation.
Mortality	Day 90	Assess the mortality since hospitalization
Assessment of the severity of ARDS	7 days	the severity of ARDS will be assessed regarding duration of non-invasive and invasive ventilation

Countries

France

Outcome results