Chronic Obstructive Pulmonary Disease
Conditions
Keywords
Continuous monitoring
Brief summary
For patients admitted to the medical ward, it is often difficult to predict if their clinical condition will deteriorate, however subtle changes in vital signs are usually present 8 to 24 hours before a life-threatening event such as respiratory failure leading to ICU admission, or unanticipated cardiac arrest. Such adverse trends in clinical observations can be missed, misinterpreted or not appreciated as urgent. New continuous and wearable 24/7 clinical vital parameter monitoring systems offer a unique possibility to identify clinical deterioration before patients condition progress beyond the point-of-no-return, where adverse events are inevitable. The WARD-COPD project aims to determine the correlation between cardiopulmonary micro events and clinical adverse events during the first four days after hospital admission with acute exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD).
Interventions
Patients recruited will be continuously monitored with Isansys Lifetouch patch, Isansys wireless blood pressure monitor, Nonin WristOx 3150, Empatica E4, and Radiometer TCM5 FLEX monitor.
Sponsors
Technical University of Denmark
Herlev and Gentofte Hospital
University Hospital Bispebjerg and Frederiksberg
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
* Adult patients admitted with AECOPD * Recruitment and monitoring start is possible within 24 hours after admission
Exclusion criteria
* Patient expected not to cooperate * Patient allergic to plaster, plastic or silicone * Active therapy withdrawn * Patients with dementia or not able to give informed consent * Patients with pacemaker or implantable cardioverter-defibrillator (ICD) unit * Expected discharge within less than 24 hours from possible inclusion
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Any serious adverse events | within 30 days after inclusion | E.g. cardiac arrest, ICU admission, acute myocardial infarction, stroke, sepsis, acute kidney injury or other serious adverse events (defined in Protocol Appendix A) |
Secondary
| Measure | Time frame |
|---|---|
| Mortality | within 6 months after inclusion |
| Readmission | within 6 months after inclusion |
Countries
Denmark
Outcome results
None listed