Assessment of the Outcome of Endodontic Treatment Using Cone Beam Computed Tomography.

Assessment of the Outcome of Endodontic Treatment Using Cone Beam Computed Tomography-A Prospective Study

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03660163

Enrollment

Registered

2018-09-06

Start date

2016-11-01

Completion date

2019-08-01

Last updated

2018-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periapical Periodontitis

Brief summary

The aim of the study is to assess the correlation between pre-obturation bacterial detection using fluorescence amplification and outcome of endodontic treatments. Thus, enabling a suitable detection threshold to predict the likelihood of treatment failure. This has the potential to be used a bench side tool in general dental practice to act as a surrogate endpoint for clinicians performing root canal treatment.

Detailed description

Pre-obturation root canal samples were taken using paper points from patients undergoing primary root treatments. The samples were analyzed using a fluorescent spectrometer and a molecular fluorescent vital dye (Calcein AM). Pre-operative and 1-year post-operative periapical radiographs and Cone Beam Computed Tomography (CBCT) scans were assessed by two calibrated expert examiners to evaluate the outcome of the root canal treatments. The use of a chairside bacterial stain can allow the clinician to predict the outcome of treatment with confidence. Sampling the root canal space with endodontic paper points followed by ex-situ fluorescent staining and analysis provides a patient-friendly, simple to use and rapid way of predicting root canal treatment outcome.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients with at least one tooth diagnosed with the endodontic disease. * teeth that were tender to percussion and palpation. * teeth that had a sinus tract and/ swelling. * Both primary treatment teeth and teeth which had already been root treated were considered.

Exclusion criteria

* Patients were excluded if they were pregnant. * Immunosuppressed patients. * Non-restorable teeth. * Teeth with a periodontal probing depth greater than 3mm. * Teeth with apical radiolucencies with the longest dimension above 1.2cm.

Design outcomes

Primary

Measure	Time frame	Description
Periapical periodontium health	One year	Assess the health of periapical periodontium of a tooth by examining the CBCT image

Outcome results