Efficacy of Antimicrobial Coating Suture Coated Vicryl Plus Compared With Vicryl in Reduced Surgical Site Infection of Dental Implant Surgeries: A Uni-Blind Randomized Clinical Trial Study

Vicryl Plus and Vicryl Sutures in Reduce of Infection in Dental Implant Surgery

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03659344

Enrollment

320

Registered

2018-09-06

Start date

2016-09-01

Completion date

2018-07-30

Last updated

2018-09-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infection, Surgical Site

Keywords

sutures, Surgical Wound Infection, Polyglactin 910

Brief summary

Patients randomly aligned in 2 groups.Vicryl plus sutures were used in group 1 for closing subperiostal flaps after dental implant surgeries and vicryl sutures were used in group 2.

Detailed description

Patients were divided randomly based on computer randomization list in two groups: In group1, vicryl plus 4-0 (Vicryl Plus Ethicon,Johnson & Johnson Company, Sommerville, NJ) suture was used to close surgical site and Vicryl 4-0 (Vicryl Ethicon,Johnson & Johnson Company, Sommerville, NJ) in group II. All dental implants were placed through creating subperiosteal flaps. In each group, fresh socket placed dental implants were documented. Patients were visited in 1, 2, 3 and 4 weeks after dental implant surgeries. Postoperative infection was defined as local erythematous change in the sutured wound with purulent discharge or localized abscess formation on surgical site. If wound dehiscence occurred, it was documented. Patients were blind about what suture was used.

Interventions

DRUGVicryl plus

Using vicryl sutures which coated with triclosan (antibiotic)

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Subject)

Masking description

Patients were blind about kind of sutures which were used to close flaps.

Intervention model description

In group1, vicryl plus suture was used to close flaps. In group2,vicryl was used to close flaps

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Need 3 dental implants at the posterior of the mandible

Exclusion criteria

* Diabetic patients * smoker * poor oral hygiene

Design outcomes

Primary

Measure	Time frame	Description
The prevalence of post-operative infection	In one month	The number of participants who had local erythematous change in the sutured wound with purulent discharge or localized abscess formation on surgical site.
The prevalence of post-operative dehiscence	In one month	The number of participants who had relatively or completely open wound

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026