Acute Coronary Syndrome, Atrial Fibrillation
Conditions
Keywords
Acute Coronary Syndrome, Atrial Fibrillation, Percutaneous Coronary Intervention
Brief summary
ACS are a potent risk factor for AF, with new onset AF occurring in up to 1 in every 5 patients hospitalized with an ACS. Despite its relatively frequent occurrence and the many etiologic factors involved in its pathogenetic condition, the frequency and prognostic significance of AF complicating ACS remain unclear
Detailed description
There are limited data available, particularly from a representative population-based perspective describing recent pharmacological and non-pharmacological management and clinical event rates associated with AF complicating ACS in the era of novel treatment strategies (in both AF and ACS) and high coronary reperfusion rates. This registry will assess the current in-hospital management and clinical events at 6 months of consecutive patients admitted in Italian cardiology intensive care units (CCUs) for an ACS treated invasively with PCI and stent implantation who present AF at admission or during hospital stay, before or after stent implantation .
Interventions
OTHERAcute coronary syndrome and PCI and AF
Patient with ACS and ACS treated with PCI
Sponsors
Heart Care Foundation
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* All consecutive ACS patients treated with PCI with stent implantation who present AF at admission or during hospital stay, before or after stent implantation.
Exclusion criteria
* Patients admitted with a diagnosis of ACS at the time of enrolment but not confirmed during hospitalization * ACS treated medically or with PCI but without stent implantation * Patients not giving informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Clinical epidemiology | Enrollement | Demographics |
| Management | 6 months | Pharmacological treatment |
| Antithrombotic strategy | 6 months | Intravenous or oral antiplatelet and anticoagulation therapies and their combination |
| Number of procedure performed on enrolled patients | 6 months | In-hospital management |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pharmacological therapies | 6 months | Use and persistence of therapies prescribed at discharge |
| Clinical outcomes | 6 months | All cause deaths, major bleedings, non fatal stroke, systemic embolism, transiet ischemic attach, MI recurrence |
Countries
Italy
Outcome results
None listed