Metabolomic Alterations in the Vascular Compartment in Patients With Sepsis

Metabolomic Alterations in the Vascular Compartment in Patients With Sepsis - an Observational Study

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03655899

Acronym

METSEP

Enrollment

Registered

2018-08-31

Start date

2017-10-23

Completion date

2019-03-12

Last updated

2019-09-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endothelial Dysfunction

Keywords

metabolomics, systems biology, Sepsis

Brief summary

This study will investigate the metabolic alterations of vascular cells caused by sepsis and septic shock

Detailed description

This study will investigate the metabolic alterations of vascular cells caused by sepsis and septic shock in 60 patients

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* 18 year or older * Sepsis or Septic shock

Exclusion criteria

* Pregnant or breastfeeding * Hemoglobin ≤ 5.0 mmol/L * Platelets ≤ 5.0 mia/L * Consent not obtainable * Do not resuscitate order

Design outcomes

Primary

Measure	Time frame	Description
Shock induced endotheliopaty	Up to 30 days	Mortality

Countries

Denmark

Outcome results