COPD
Conditions
Brief summary
Chronic Obstructive Pulmonary Disease (COPD) is a major public health problem and is expected to become the 3rd leading cause of death globally by 2020. The main risk factor is tobacco. Tobacco poisoning is found in 80 to 90% of patients with COPD. However, non-smoking COPD is also described, with increasing prevalence figures, particularly related to occupational exposure, especially among farmers.
Detailed description
A prospective screening study based on questionnaires and electronic mini-spirometry (Néo-6®) that includes a representative sample of dairy farmers from the departments of Morbihan and Île-et-Vilaine in Brittany. The dairy farmers had an occupational medicine appointment and, if they demonstrated at least one marker of possible bronchial obstruction (chronic cough, chronic bronchitis, dyspnoea, wheezing, spirometry), they were referred to a pulmonologist.
Interventions
OTHERquestionnaires and electronic mini-spirometry
prospective screening study based on questionnaires and electronic mini-spirometry (Néo-6(®)) that includes a representative sample of dairy farmers from the departments of Morbihan and Île-et-Vilaine in Brittany
Sponsors
Rennes University Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* dairy farmers from the departments of Morbihan and Île-et-Vilaine in Brittany * control: non farmer
Exclusion criteria
* pigs or grain farmers * Pregnant women * oral corticosteroids or immunosuppressive drugs
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Level of bronchial obstruction | 3 years | Respiratory specific indices are extracted from a screening spirometry : Forced expiratory volume in one second (FEV1) Forced Vital Capacity (FVC) Bronchial obstruction is stated with a ratio FEV1 / FVC \< 0.8 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Prevalence of occupational specific COPD in dairy farmers | 3 years | Occupational specific COPD is defined as a ratio FEV1 / FVC \< 0.8 associated to a clinical situation : * non reversibility after β2-agonists or corticoids administration, * no personal nor familial allergic conditions, * smoking history \< 1 cigarettes package per year. |
Countries
France
Outcome results
None listed