Exercise Intervention for Patients With Sarcopenia or Frailty in Long-term Care Institutions

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03650907

Enrollment

Registered

2018-08-29

Start date

2018-08-24

Completion date

2019-05-31

Last updated

2019-08-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sarcopenia

Brief summary

Sarcopenia is a geriatric syndrome of decreased muscle volume with muscular function decline. There is more tendency for sarcopenic elderly to be frail, disabled, or have cardiovascular disease. Compared to those who are not sarcopenic, they also had worse prognosis in response to treatment for definite diseases, and spend more medical cost. Exercise appears to have an important role in management of sarcopenia. In the current study, the investigators provide an exercise program, including resistance/balance training for the elderly with sarcopenia or frailty in long-term care institution, and evaluate the effect.

Interventions

BEHAVIORALGroup exercise program

Patients in experimental group attend group exercise program, instructed by fitness trainer, at long-term care institutions. Frequency: 3 times per week. Type: resistance/flexibility/balance training, including warm-up and cold-down. Duration: 1 hour per time, for 16 weeks.

BEHAVIORALSelf exercise program

Patients in control group receive oral education for self exercise program, mainly resistance muscle training. Patients are requested to do self-training for 16 weeks.

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

20 Years to 110 Years

Healthy volunteers

Inclusion criteria

1. \>20-year-old 2. diagnosed with sarcopenia (by the definition from Asia workgroup for sarcopenia, AWGS) or frailty (The Fried model, based on five functional criteria)

Exclusion criteria

1. Severe medical diseases or mental problems, which result in difficulty to follow exercise program. 2. Inability to get down from bed for activity due to disease, such as neuropathy or orthopedic disease. 3. High risk group for exercise program, such as those with unstable fracture or nonunion fracture. 4. Anyone who didn't want attend this study.

Design outcomes

Primary

Measure	Time frame	Description
Muscle strength	after 16-weeks training	grasp strength by dynamometer
walk speed	after 16-weeks training	6-meter walk test

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026