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Effects of Yoga, Strength Training and Aerobic Exercise on Cognition in Adult Cancer Survivors

Effects of Yoga, Strength Training and Aerobic Exercise on Cognition in Adult Cancer Survivors

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03650322
Enrollment
78
Registered
2018-08-28
Start date
2018-10-01
Completion date
2020-05-30
Last updated
2023-07-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer, Cancer-related Problem/Condition, Exercise

Brief summary

The investigators propose to compare the effects of a 12-week, supervised, site-based group yoga intervention on cognitive function, functional fitness, and well-being in middle-aged cancer survivors. Subjects will be randomly assigned to one of three exercise conditions: a yoga group, an aerobic walking group or a strength training group. All sessions (2-3 times per week) will be led by a trained exercise leader for a total of 150 minutes of exercise each week for the 12-week intervention.

Interventions

BEHAVIORALYoga

12 weeks, total of 150 minutes of exercise per week.

12 weeks, total of 150 minutes of exercise per week.

BEHAVIORALAerobic Walking

12 weeks, total of 150 minutes of exercise per week.

Sponsors

University of Illinois at Urbana-Champaign
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
30 Years to 70 Years
Healthy volunteers
Yes

Inclusion criteria

* 30-70 years of age * Cancer diagnosis * 1 year since last cancer treatment (surgery, chemotherapy, and/or radiation) * Not planning to receive treatment during study period * Completion of Physical Activity Readiness Questionnaire (PAR-Q) * Ambulatory and absence of health conditions that may be exacerbated by yoga, walking, or strength training * Physician consent (if deemed necessary) * Low-active, i.e. less than 150 minutes/week of moderate to vigorous exercise, no current yoga practice (including within last six months) * Intention to remain in the Champaign-Urbana area over the study duration * Willingness to be randomly assigned to one of the three groups (yoga, aerobic walking, strength training) * Comfortable with reading, writing, and speaking English

Exclusion criteria

* Below 30 or above 70 years of age * Cancer diagnosis of the brain * Less than 1 year since last treatment (surgery, chemotherapy, and/or radiation) or plans to receive treatment during study * Determined ambulatory or 'high risk' based on responses to PAR-Q * High-active (exercising more than 150 minutes/week in the last six months) * No consent from physician * Intent to be away from the Champaign-Urbana area for an extended period of time during the study * Inability to communicate effectively in English

Design outcomes

Primary

MeasureTime frameDescription
Cognitive FunctionChange from baseline to 12 weeks will be reportedParticipants will complete part of the NIH Toolbox measures that assess cognitive function.

Secondary

MeasureTime frameDescription
Cardiovascular FunctionChange from baseline to 12 weeks will be reportedParticipants will complete a submaximal exercise test to reach a target heart rate within 85% of the age-predicted maximum.

Other

MeasureTime frameDescription
Feasibility: Recruitment and retention ratesBaseline to 12-weeksProportion of participants randomized relative to total contacts, Proportion of participants who complete follow-up questionnaires,

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 17, 2026