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Relation Between PRST Score, Skin Conductance and BIS

The Relation Between PRST Score, Skin Conductance and BIS Values During Anesthesia

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03650283
Acronym
RB
Enrollment
50
Registered
2018-08-28
Start date
2019-03-04
Completion date
2019-05-31
Last updated
2019-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Awakeness, Pain

Brief summary

Determine the relation between PRST (pressure, rate, sweating, tears) score, skin conductance (SC) and Bispectral index (BIS) values during anesthesia

Detailed description

Probability of \>0 points in the PRST as a function of BIS and number of fluctuations in mean skin conductance (NFSC) will be recorded during the anesthesia.

Interventions

OTHERmonitoring

The bispectral index (BIS) and skin conductance (SC) monitors will be connected when patient will be positioned on the operating table. A BIS value greater than 60 will be considered an indicator of light anaesthesia. The SC monitoring will be achieved using the MEDSTORM AS 2005 monitor. Number of fluctuations in mean skin conductance (NFSC) of \>0.1 s-1 in a period of 15 s might be counted as a significant change and indicates an increase in the sympathetic outflow. General anaesthesia will be performed and laryngeal mask will be inserted. Blood pressure, heart rate, BIS, SC, and PRST (pressure, rate, sweating, tears) score will be recorded.

Sponsors

Diskapi Yildirim Beyazit Education and Research Hospital
Lead SponsorOTHER_GOV

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Minor elective surgery * General anaesthesia

Exclusion criteria

* autonomic neuropathy * presence of a pacemaker * medication with anticholinergic drugs * use of ketamine, clonidine

Design outcomes

Primary

MeasureTime frameDescription
Correlation between NFSC, PRST and BISanesthesia induction (while giving induction agent to the patient), surgical incision (when the surgeon makes the first incision), extubation (when LMA is removed)Correlation between NFSC-PRST and, BIS-PRST will be assessed.

Contacts

Primary ContactBahar SAKIZCI UYAR
drsakizciuyar@gmail.com5057000240

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026