Ovary; Anomaly
Conditions
Brief summary
Increasing interest has emerged concerning ovarian tissue cryopreservation and subsequent transplantation as a potential way of preserving fertility in cancer patients as well as for women who just wish to delay childbearing. As the majority of existing protocols use the slow freezing method, this study aims to test vitrification techniques of ovarian cortex.
Interventions
OTHERVitrification
Vitrification of ovarian tissue
Sponsors
Maximilian Franz, M.D.
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Intervention model description
Vitrification of ovarian tissue
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* female-to-male transsexuals * gender completing operation * signed informed consent form * willingness to donate ovarian tissue for research purposes * age \>=18 years
Exclusion criteria
* malignant disease * age under 18 years * refusal to donate ovarian tissue
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| survival of ovarian tissue | 2 days until 2 years after freezing | histologic and enzymatic evaluation of ovarian tissue with respect to survival and functionality of ovarian follicles |
Countries
Austria
Contacts
Primary ContactJulian Marschalek, MD
Backup ContactDetlef Pietrowski, Dr.
Outcome results
None listed