Adenocarcinoma of the Esophagogastric Junction, Fluorescence Laparoscopy
Conditions
Keywords
fluorescence laparoscopy, adenocarcinoma of the esophagogastric junction (AEG)
Brief summary
The fluorescent laparoscopic technique would be applied to the radical resection of gastric cancer at the junction of esophagus and stomach, and compared with the traditional laparoscopic radical resection of gastric cancer to find a better surgical method for patients
Interventions
PROCEDUREfluorescent laparoscopic radical gastrectomy
The gastrectomy for group F would be underwent by the fluorescence laparoscopy. All surgical procedures will be performed by the surgery team ,which is leaded by professor Wang Quan.
PROCEDUREtraditional laparoscopic radical gastrectomy
The gastrectomy for group L would be underwent by the laparoscopy.All surgical procedures will be performed by the surgery team ,which is leaded by professor Wang Quan.
Sponsors
Dong Yang
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
\- 1. All cases should be diagnosed as adenocarcinoma of the esophagogastric junctionncer by histology. The tumor is within 1 cm above or 2 cm below the anatomic cardia. The clinical stage is T1-3, Nx, M0 for gastric cancer which can undergo the laparoscopic surgery. 2\. Eastern Cooperative Oncology Group (ECOG) scale 0-2 3. Heart, lung, liver, and kidney function can tolerate operation 4. Patients and their families are able to understand and be willing to participate in this clinical study and to sign informed consent.
Exclusion criteria
1\. history of stomach malignant disease 2. recent diagnosis of other malignant tumors (except for papillary carcinoma of the thyroid gland and basal cell carcinoma of the skin) 3. patients with obstruction, perforation, bleeding requiring emergency surgery 4. a history of abdominal surgery (which makes it difficult to perform laparoscopic procedures), severe systemic disease such as diabetes, severe chronic lung disease, cirrhosis, other malignant diseases 5. combined stomach multiple carcinomas 6. with a history of serious mental illness 7. pregnant or lactating women 8. The researchers believe that the patients are unsuitable to participate in the researchers with other cases. \-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the number of the dissected lymph nodes | in the perioperative period | It includes the total number of the dissected lymph nodes and every group of lymph nodes |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| the incidence of complications | one month after surgery | — |
| the operation time | in the perioperative period | The descriptive name of unit would be minute (min). |
| the blood loss during the operation | in the perioperative period | The descriptive name of unit would be millilitre (ml). |
| 3-year disease-free survival | three years after operation] | — |
| cases converted to open surgery | in the perioperative period | — |
| The mean postoperative hospital stay | in the perioperative period | The descriptive name of unit would be day (d). |
| Postoperative recovery of intestinal peristalsis | in the perioperative period | The descriptive name of unit would be hour (h). |
Countries
China
Contacts
Primary ContactDong Yang, Master
Backup ContactQuan Wang, Doctor
Outcome results
None listed