Chronic Obstructive Pulmonary Disease
Conditions
Brief summary
This is a prospective multicenter cohort study which includes all consecutive COPD patients who come for a visit in one the participating pneumologist. They will have to do a sputum and to complete some questionnaries. Questionnaries will be redone by phone after 1 and 3 months and during the visit after 6 months. We will correlate aspergillus presence in sputum with quality of life (QoL), and COPD symptoms evaluated by questionnaires.
Detailed description
Aspergillosis disease is a growing problem. These diseases are not yet uncommon in chronic obstructive pulmonary disease patients. (COPD). Aspergillosis disease are very difficult to be diagnosed or treated. Isolation of aspergillus in sputum of patients is not always responsible of a real disease. Need of treatment is discussed. That is why, we will conduct a prospective cohort study to evaluate aspergillus rate in respiratory samples of COPD patients (GOLD stage III or IV)
Interventions
DIAGNOSTIC_TESTQuestionnaries
patients will have to do a sputum and to complete some questionnaries
Sponsors
Centre Hospitalier Universitaire, Amiens
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* COPD patients GOLD stage III and IV
Exclusion criteria
* Cystic fibrosis * Pulmonary fibrosis * hematological malignancy * known aspergilloma * allergic bronchopulmonary aspergillosis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| presence of aspergillus in sputum or respiratory samples | one year before inclusion | sputum examination |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Dyspnea with MMRC score | day of inclusion | Pulmonary function testing |
Countries
France
Outcome results
None listed