Chronic Periodontitis
Conditions
Brief summary
The aim of this study is to find out if one blood group phenotype is more responsive than the others to the nonsurgical periodontal treatment.
Detailed description
To the best of our knowledge, this is the first (research) randomized clinical trial that assesses how patient respond to the nonsurgical periodontal treatment based on their blood group phenotype.
Interventions
PROCEDUREnonsurgical periodontal treatment
patients will undergo nonsurgical periodontal treatment to reduce the relative attachment level and improve the probing depth. An initial session will be conducted to remove supra gingival plaque and calculus. another appointment is set to perform full moth scalling and root planing.
Sponsors
Damascus University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* systematically healthy. * have at least 20 teeth excluding the third molars. * had not received any periodontal treatment or antibiotic therapy for dental or medical reason 6 month prior to the study. * diagnosed with generalized chronic periodontitis (\>30% of the sites have probing depth ≥4), and a minimum of six teeth with probing depth of 5-6 mm.
Exclusion criteria
* smokers and alcoholics. * pregnancy. * history of a systematic disease such as diabetes, leukemia, epilepsy. * participants who are unable to perform routine oral hygiene. * use of orthodontic appliances. * participants who are unable to perform routine oral hygiene.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in relative attachment level. | measures will be taken at baseline and after two months from treatment. | the relative attachment level measures the length form the base of the periodontal pocket to a stent |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in periodontal probing depth. | measures will be taken at baseline and after two months from treatment. | the distance between the gingival margin to the base of the periodontal pocket. |
| Change in gingival index | index will be taken at baseline and after two months from treatment. | it is used to designate the level of the gingival inflammation. |
| Change in plaque Index | index will be taken at baseline and after two months from treatment. | it is used to designate the level of plaque accumulation. |
Countries
Syria
Outcome results
None listed